Results 121 to 130 of about 7,336,560 (297)
Standards for Reporting Qualitative Research: A Synthesis of Recommendations
Bridget C. O’Brien+4 more
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Synthesis of Vitamin A by a Marine Diaton (Nitzschia closterium W Sm.) growing in Pure Culture [PDF]
Henry Lyster Jameson+2 more
openalex +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
On the Synthesis of 3-Alkyl-4-hydroxycarbostyrils
Tatsuo Ohta, Yo Mori
openalex +2 more sources
The Role of the Liver in Hippuric Acid Synthesis [PDF]
E. Lackner+2 more
openalex +1 more source