Results 131 to 140 of about 12,303,072 (355)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

On the connection between sets of operator synthesis and sets of spectral synthesis for locally compact groups [PDF]

open access: yesarXiv, 2004
We extend the results by Froelich and Spronk and Turowska on the connection between operator synthesis and spectral synthesis for A(G) to second countable locally compact groups G. This gives us another proof that one-point subset of G is a set of spectral synthesis and that any closed subgroup is a set of local spectral synthesis.
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Ancilla-free Reversible Logic Synthesis via Sorting [PDF]

open access: yesarXiv, 2016
Reversible logic synthesis is emerging as a major research component for post-CMOS computing devices, in particular Quantum computing. In this work, we link the reversible logic synthesis problem to sorting algorithms. Based on our analysis, an alternative derivation of the worst-case complexity of generated reversible circuits is provided. Furthermore,
arxiv  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Direct Observations of Twin Formation Dynamics in Binary Semiconductors

open access: yesACS Nanoscience Au, 2021
Marcus Tornberg   +6 more
doaj   +1 more source

Advanced Datapath Synthesis using Graph Isomorphism [PDF]

open access: yesarXiv, 2017
This paper presents an advanced DAG-based algorithm for datapath synthesis that targets area minimization using logic-level resource sharing. The problem of identifying common specification logic is formulated using unweighted graph isomorphism problem, in contrast to a weighted graph isomorphism using AIGs.
arxiv  

Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]

open access: yes, 2015
A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A.   +3 more
core  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

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