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Nature Biotechnology, 2023 This article examines the practice of synthetic biology, and its relevance in terms of technoscientific responses to the Anthropocene. The article offers a brief history of the practice, and contextualises synthetic biology within the wider field of controversial ‘technofixes’ that are proposed for ameliorating the existential challenge that is the ...
英城 小林
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Principles of synthetic biology [PDF]
Essays in Biochemistry, 2021 In synthetic biology, biological cells and processes are dismantled and reassembled to make novel systems that do useful things. Designs are encoded by deoxyribonucleic acid (DNA); DNA makes biological (bio-)parts; bioparts are combined to make devices ...
K. Garner
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Synthetic biology—putting engineering into biology [PDF]
Bioinformatics, 2006 Abstract Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we review the case for this emerging discipline.
Matthias Heinemann, Sven Panke
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Synthetic biology-inspired development of live attenuated influenza vaccines [PDF]
npj VaccinesLive attenuated influenza vaccines (LAIVs) provide robust, cross-protective immunity but have traditionally been developed empirically and are associated with safety concerns.
Qisi Zhang +14 more
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Synthetic biology in plants. [PDF]
Plant Biotechnol (Tokyo)Synthetic biology, an interdisciplinary field at the intersection of engineering and biology, has garnered considerable attention for its potential applications in plant science. By exploiting engineering principles, synthetic biology enables the redesign and construction of biological systems to manipulate plant traits, metabolic pathways, and ...
Hayakawa T +3 more
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Applications of synthetic biology in medical and pharmaceutical fields
Signal Transduction and Targeted Therapy, 2023 Synthetic biology aims to design or assemble existing bioparts or bio-components for useful bioproperties. During the past decades, progresses have been made to build delicate biocircuits, standardized biological building blocks and to develop various ...
Xu Yan +3 more
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Recent Advances in CRISPR-Cas Technologies for Synthetic Biology
Journal of Microbiology, 2023 With developments in synthetic biology, “engineering biology” has emerged through standardization and platformization based on hierarchical, orthogonal, and modularized biological systems.
Song Hee Jeong, Ho Joung Lee, S. J. Lee
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Enabling technology and core theory of synthetic biology
Science China Life Sciences, 2023 Synthetic biology provides a new paradigm for life science research (“build to learn”) and opens the future journey of biotechnology (“build to use”).
Xian-En Zhang +10 more
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Synthetic Biology, 2023 AbstractSynthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.
Ibrahim Aldulijan +12 more
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Synthetic biology: Learning the way toward high-precision biological design
PLoS Biology, 2023 Since its inception, synthetic biology has overcome many technical barriers but is at a crossroads for high-precision biological design. Devising ways to fully utilize big biological data may be the key to achieving greater heights in synthetic biology.
Shohei Kitano +3 more
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