Results 11 to 20 of about 484,138 (208)

Synthetic Biology: Caught Between Property Rights, the Public Domain, and the Commons [PDF]

open access: yes, 2006
Synthetic biologists aim to make biology a true engineering discipline. In the same way that electrical engineers rely on standard capacitors and resistors, or computer programmers rely on modular blocks of code, synthetic biologists wish to create an ...
Boyle, James, Rai, Arti K.
core   +4 more sources

Grounding knowledge and normative valuation in agent-based action and scientific commitment [PDF]

open access: yes, 2018
Philosophical investigation in synthetic biology has focused on the knowledge-seeking questions pursued, the kind of engineering techniques used, and on the ethical impact of the products produced.
A Clark   +50 more
core   +1 more source

Synthetic biology and microdevices : a powerful combination [PDF]

open access: yes, 2013
Recent developments demonstrate that the combination of microbiology with micro-and nanoelectronics is a successful approach to develop new miniaturized sensing devices and other technologies.
Marchal, Kathleen   +2 more
core   +2 more sources

TinkerCell: Modular CAD Tool for Synthetic Biology [PDF]

open access: yes, 2009
Synthetic biology brings together concepts and techniques from engineering and biology. In this field, computer-aided design (CAD) is necessary in order to bridge the gap between computational modeling and biological data. An application named TinkerCell
Bergmann, Frank T.   +2 more
core   +4 more sources

Accurate prediction of gene feedback circuit behavior from component properties [PDF]

open access: yes, 2007
A basic assumption underlying synthetic biology is that analysis of genetic circuit elements, such as regulatory proteins and promoters, can be used to understand and predict the behavior of circuits containing those elements. To test this assumption, we
Alon U   +6 more
core   +2 more sources

Editorial–Synthetic Biology [PDF]

open access: yesNucleic Acids Research, 2010
Synthetic biology builds upon over 35 years of genetic engineering. For example, in the 1970s methods were invented for using enzymes to rework DNA. Applying these tools, bacteria were engineered to yield relevant products such as growth hormones and insulin.
James J. Collins   +3 more
openaire   +3 more sources

Chemical communication between synthetic and natural cells: a possible experimental design [PDF]

open access: yes, 2013
The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the synthesis of one or ...
D'Angelo, Francesca   +5 more
core   +3 more sources

Synthetic biology, patenting, health and global justice [PDF]

open access: yes, 2012
Many microbial secondary metabolites are of high biotechnological value for medicine, agriculture, and the food industry. Bacterial genome mining has revealed numerous novel secondary metabolite biosynthetic gene clusters, which encode the potential to ...
Belt, H., van den
core   +8 more sources

Synthetic biology's flywheel [PDF]

open access: yesEMBO reports, 2012
Producing drugs and chemicals efficiently from cells remains a major challenge. Synthetic biologists need to invent the equivalents of the crank and flywheel to improve productivity.
openaire   +3 more sources

A case study in model-driven synthetic biology [PDF]

open access: yes, 2008
We report on a case study in synthetic biology, demonstrating the modeldriven design of a self-powering electrochemical biosensor. An essential result of the design process is a general template of a biosensor, which can be instantiated to be adapted ...
B.M. Willardson   +6 more
core   +2 more sources

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