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Synthetic biology—putting engineering into biology [PDF]
Bioinformatics, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
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Nature Reviews Genetics, 2005 Chemistry is a broadly powerful discipline in contemporary science because it has the ability to create new forms of the matter that it studies. By doing so, chemistry can test models that connect molecular structure to behaviour without having to rely on what nature has provided.
Benner, Steven A., Sismour, A. Michael
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Synthetic Biology, 2023 AbstractSynthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.
Ibrahim Aldulijan +12 more
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Applications, challenges, and needs for employing synthetic biology beyond the lab
Nature Communications, 2021 Synthetic biology holds great promise for addressing global needs. However, most current developments are not immediately translatable to ‘outside-the-lab’ scenarios that differ from controlled laboratory settings.
Sierra M. Brooks, H. Alper
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Journal of Integrative Plant Biology, 2022 Plant natural products have been extensively exploited in food, medicine, flavor, cosmetic, renewable fuel and other industrial sectors. Synthetic biology has recently emerged as a promising means for cost-effective and sustainable production of natural ...
Xinyu Liu +3 more
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ACS Synthetic Biology, 2022 As redesigning organisms using engineering principles is one of the purposes of synthetic biology (SynBio), the standardization of experimental methods and DNA parts is becoming increasingly a necessity.
K. Malcı +14 more
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A synthetic transcription platform for programmable gene expression in mammalian cells
Nature Communications, 2022 Precise and scalable regulation of gene expression in mammalian cells is challenging. Here, the authors created a highly tunable CRISPR-based synthetic transcription system for programmable control of mammalian gene expression and cellular activity.
William C. W. Chen +13 more
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Synthetic Biology and Computer-Based Frameworks for Antimicrobial Peptide Discovery.
ACS Nano, 2021 Antibiotic resistance is one of the greatest challenges of our time. This global health problem originated from a paucity of truly effective antibiotic classes and an increased incidence of multi-drug-resistant bacterial isolates in hospitals worldwide ...
M. D. Torres +4 more
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Org. Biomol. Chem., 2010 There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic approach to improving and increasing the programmability and robustness of biological components is
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