Results 11 to 20 of about 927,045 (311)

Genomics and synthetic biology as a viable option to intensify sustainable use of biodiversity [PDF]

open access: yes, 2011
The Amazon basin is an area of mega-biodiversity. Different models have been proposed^1-8^ for the establishment of an effective conservation policy, increasing sustainability and adding value for biodiversity. Currently, a broad spectrum of technologies
Elibio L. Rech
core   +3 more sources

Engineering orthogonal dual transcription factors for multi-input synthetic promoters [PDF]

open access: yes, 2016
Synthetic biology has seen an explosive growth in the capability of engineering artificial gene circuits from transcription factors (TFs), particularly in bacteria. However, most artificial networks still employ the same core set of TFs (for example LacI,
Broedel, AK, Isalan, M, Jaramillo, A
core   +2 more sources

Molecular and biochemical characterization of a novel isoprene synthase from Metrosideros polymorpha

open access: yesBMC Plant Biology, 2018
Background Isoprene is a five-carbon chemical that is an important starting material for the synthesis of rubber, elastomers, and medicines. Although many plants produce huge amounts of isoprene, it is very difficult to obtain isoprene directly from ...
Soo-Jin Yeom   +8 more
doaj   +1 more source

Chemical communication between synthetic and natural cells: a possible experimental design [PDF]

open access: yes, 2013
The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the synthesis of one or ...
D'Angelo, Francesca   +5 more
core   +3 more sources

A synthetic microbial biosensor for high-throughput screening of lactam biocatalysts

open access: yesNature Communications, 2018
Efficient biosynthesis of lactams is still undesirable due to lacking of suitable enzyme. Here, the authors develop a sensitive transcription factor-based biosensor for high-throughput screening of marine metagenome and find a cyclase that can cyclize ω ...
Soo-Jin Yeom   +10 more
doaj   +1 more source

Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage

open access: yesNature Communications, 2022
Secreted proteins, such as hormones or cytokines, are key mediators in multicellular organisms. Here the authors present two genetically encoded orthogonal regulatory secretion systems that enables inducible protein release and construction of logic ...
Arne Praznik   +8 more
doaj   +1 more source

Synthetic biology, engineering biology, market expectation

open access: yesEngineering Biology, 2020
‘Engineering biology’ is being increasingly adopted as a term by organisations that seek to deliver benefits from ‘synthetic biology’. However, are ‘engineering biology’ and ‘synthetic biology’ different words with the same meaning or do they signal ...
Lionel Clarke
doaj   +1 more source

"Poppy" yeast [PDF]

open access: yes, 2015
I am old enough to have taken part in the international project to sequence the first eukaryotic genome—that of Saccharomyces cerevisiae—which was released in 1996. Twenty years later, scientists from academic and commercial institutions are now involved
RINALDI, Teresa
core   +1 more source

Genome-scale model of C. autoethanogenum reveals optimal bioprocess conditions for high-value chemical production from carbon monoxide

open access: yesEngineering Biology, 2019
Clostridium autoethanogenum is an industrial microbe used for the commercial-scale production of ethanol from carbon monoxide. While significant progress has been made in the attempted diversification of this bioprocess, further improvements are ...
Rupert O.J. Norman   +13 more
doaj   +1 more source

Opening up the Future(s) of Synthetic Biology [PDF]

open access: yes, 2013
Much of the discussion surrounding synthetic biology involves some degree of speculation about the future. This paper reports on two workshops we held with the aim of ‘opening up’ and exploring possible futures for synthetic biology, one at the Synthetic
Calvert, Jane, Frow, Emma
core   +1 more source

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