Results 221 to 230 of about 2,952,613 (401)

Synthetic biology in the UK – An outline of plans and progress

, 2016
Lionel Clarke, R.I. Kitney
openalex   +1 more source

A navigation guide of synthetic biology tools for Pseudomonas putida.

Biotechnology Advances, 2021
Maria Martin-Pascual, C. Batianis, Lyon Bruinsma, Enrique Asin-Garcia, Luis Garcia-Morales, R. Weusthuis, Richard van Kranenburg, Vitor A. P. Martins dos Santos   +7 more
semanticscholar   +1 more source

Synthetic Biology

, 2017
‘What is life?’ One of the most intriguing and difficult questions to answer. Richard Feynman argued that ‘Everything that living systems do is done by atoms that act according to the laws of physics’, and this is the basis we (all) build on. Today, it is still difficult to define life, even at the cellular scale. At the molecular level, however, it is
Poolman, Berend, Noireaux, Vincent
openaire   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Unveiling the Frontiers of Synthetic Biology in Brazil: Pioneering the National Synthetic Biology Network. [PDF]

ACS Omega
Santos LV, Maklouf GR, do Nascimento CZS, Lins MRCR, Rezende JC, Rojas CA, Sampaio Y, El Kadri NK, Kundlatsch GE, Simão RCG, Rech EL, Silva LF, Pedrolli DB.   +12 more
europepmc   +1 more source

Special issue: Plant synthetic biology

, 2020
Dhirendra Kumar, Yves Van de Peer
openalex   +1 more source

Improvement of Biomedical Structural Polymers by Synthetic Biology Methods

, 2021
Vyacheslav Gennad'evich Malyutin, Valentina Olegovna Sevagina, Viktor Anatolevich Kokotov, Vitaly V. Goncharov, Alexander Markov, Karina Nikolaevna Shalneva   +5 more
openalex   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Identification and application of bioparts for plant synthetic biology. [PDF]

Mol Cells
Koo H, Jung M, Lee S, Go S, Kim YM.
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source