Results 221 to 230 of about 435,061 (337)

Genomics and synthetic biology as a viable option to intensify sustainable use of biodiversity [PDF]

, 2011
Elíbio Rech
openalex   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Do the Shuffle: Expanding the Synthetic Biology Toolkit for Shufflon-like Recombination Systems. [PDF]

ACS Synth Biol
Katalinić J, Richards M, Auyang A, Millett JH, Kogenaru M, Windbichler N.   +5 more
europepmc   +2 more sources

Bacterial DNA methylases as novel molecular and synthetic biology tools: recent developments. [PDF]

Appl Microbiol Biotechnol
Flores-Fernández CN, O'Callaghan CA.
europepmc   +1 more source

Recent patent applications in synthetic biology [PDF]

, 2011

openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Engineering a New Generation of Gene Editors: Integrating Synthetic Biology and AI Innovations. [PDF]

ACS Synth Biol
Chia BS, Seah YFS, Wang B, Shen K, Srivastava D, Chew WL.   +5 more
europepmc   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

The Importance of Biosecurity in Emerging Biotechnologies and Synthetic Biology. [PDF]

Avicenna J Med Biotechnol
Soleimani Sasani M.
europepmc   +1 more source

Sustainability and Anticipatory Governance in Synthetic Biology [PDF]

, 2012
Arnim Wiek, David H. Guston, Emma Frow, Jane Calvert   +3 more
openalex   +1 more source