Results 41 to 50 of about 2,952,613 (401)
A synthetic microbial biosensor for high-throughput screening of lactam biocatalysts
Nature Communications, 2018 Efficient biosynthesis of lactams is still undesirable due to lacking of suitable enzyme. Here, the authors develop a sensitive transcription factor-based biosensor for high-throughput screening of marine metagenome and find a cyclase that can cyclize ω ...
Soo-Jin Yeom +10 more
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Engineering orthogonal dual transcription factors for multi-input synthetic promoters [PDF]
, 2016 Synthetic biology has seen an explosive growth in the capability of engineering artificial gene circuits from transcription factors (TFs), particularly in bacteria. However, most artificial networks still employ the same core set of TFs (for example LacI,
Broedel, AK, Isalan, M, Jaramillo, A
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Advances in Synthetic Biology and Biosafety Governance
Frontiers in Bioengineering and Biotechnology, 2021 Tremendous advances in the field of synthetic biology have been witnessed in multiple areas including life sciences, industrial development, and environmental bio-remediation.
Jing Li +3 more
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Synthetic Genomes for Synthetic Biology [PDF]
Journal of Molecular Cell Biology, 2010 A genome synthesized entirely from scratch has been used to replace the native genome of a living cell, thus creating a new cell. This achievement marks a new frontier in synthetic biology to design and create genomes for organisms with few genetic tools and for applications in areas of energy, health care and the environment.
openaire +2 more sources
Principles of synthetic biology
Essays in Biochemistry, 2021 In synthetic biology, biological cells and processes are dismantled and reassembled to make novel systems that do useful things. Designs are encoded by deoxyribonucleic acid (DNA); DNA makes biological (bio-)parts; bioparts are combined to make devices ...
K. Garner
semanticscholar +1 more source
Ten future challenges for synthetic biology
Engineering Biology, 2021 After 2 decades of growth and success, synthetic biology has now become a mature field that is driving significant innovation in the bioeconomy and pushing the boundaries of the biomedical sciences and biotechnology. So what comes next?
Olivia Gallup, Hia Ming, T. Ellis
semanticscholar +1 more source
Synthetic biology: biology by design [PDF]
Microbiology, 2013 Synthetic biology can be defined as the design and construction of novel biologically based parts, devices and systems, as well as the redesign of existing natural biological systems, for useful purposes. It builds on genetic engineering, being design-driven genetic engineering encompassing engineering concepts of standardization and abstraction (Endy,
Roberts, MAJ +3 more
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Nature Communications, 2022 Secreted proteins, such as hormones or cytokines, are key mediators in multicellular organisms. Here the authors present two genetically encoded orthogonal regulatory secretion systems that enables inducible protein release and construction of logic ...
Arne Praznik +8 more
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, 2015 I am old enough to have taken part in the international project to sequence the first eukaryotic genome—that of Saccharomyces cerevisiae—which was released in 1996. Twenty years later, scientists from academic and commercial institutions are now involved
RINALDI, Teresa
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Synthetic Biology: Caught Between Property Rights, the Public Domain, and the Commons [PDF]
, 2006 Synthetic biologists aim to make biology a true engineering discipline. In the same way that electrical engineers rely on standard capacitors and resistors, or computer programmers rely on modular blocks of code, synthetic biologists wish to create an ...
Boyle, James, Rai, Arti K.
core +4 more sources