Results 41 to 50 of about 2,368,722 (358)

Molecular and biochemical characterization of a novel isoprene synthase from Metrosideros polymorpha

open access: yesBMC Plant Biology, 2018
Background Isoprene is a five-carbon chemical that is an important starting material for the synthesis of rubber, elastomers, and medicines. Although many plants produce huge amounts of isoprene, it is very difficult to obtain isoprene directly from ...
Soo-Jin Yeom   +8 more
doaj   +1 more source

Modular Synthetic Biology Toolkit for Filamentous Fungi

open access: yesACS Synthetic Biology, 2021
Filamentous fungi are highly productive cell factories, often used in industry for the production of enzymes and small bioactive compounds. Recent years have seen an increasing number of synthetic-biology-based applications in fungi, emphasizing the need
László Mózsik   +5 more
semanticscholar   +1 more source

Advances in Synthetic Biology and Biosafety Governance

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Tremendous advances in the field of synthetic biology have been witnessed in multiple areas including life sciences, industrial development, and environmental bio-remediation.
Jing Li   +3 more
semanticscholar   +1 more source

Editorial–Synthetic Biology [PDF]

open access: yesNucleic Acids Research, 2010
Synthetic biology builds upon over 35 years of genetic engineering. For example, in the 1970s methods were invented for using enzymes to rework DNA. Applying these tools, bacteria were engineered to yield relevant products such as growth hormones and insulin.
James J. Collins   +3 more
openaire   +3 more sources

A synthetic microbial biosensor for high-throughput screening of lactam biocatalysts

open access: yesNature Communications, 2018
Efficient biosynthesis of lactams is still undesirable due to lacking of suitable enzyme. Here, the authors develop a sensitive transcription factor-based biosensor for high-throughput screening of marine metagenome and find a cyclase that can cyclize ω ...
Soo-Jin Yeom   +10 more
doaj   +1 more source

Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage

open access: yesNature Communications, 2022
Secreted proteins, such as hormones or cytokines, are key mediators in multicellular organisms. Here the authors present two genetically encoded orthogonal regulatory secretion systems that enables inducible protein release and construction of logic ...
Arne Praznik   +8 more
doaj   +1 more source

Ten future challenges for synthetic biology

open access: yesEngineering Biology, 2021
After 2 decades of growth and success, synthetic biology has now become a mature field that is driving significant innovation in the bioeconomy and pushing the boundaries of the biomedical sciences and biotechnology. So what comes next?
Olivia Gallup, Hia Ming, T. Ellis
semanticscholar   +1 more source

Synthetic biology 2020–2030: six commercially-available products that are changing our world

open access: yesNature Communications, 2020
Synthetic biology will transform how we grow food, what we eat, and where we source materials and medicines. Here I have selected six products that are now on the market, highlighting the underlying technologies and projecting forward to the future that ...
Christopher A. Voigt
semanticscholar   +1 more source

Synthetic biology's flywheel [PDF]

open access: yesEMBO reports, 2012
Producing drugs and chemicals efficiently from cells remains a major challenge. Synthetic biologists need to invent the equivalents of the crank and flywheel to improve productivity.
openaire   +3 more sources

Genome-scale model of C. autoethanogenum reveals optimal bioprocess conditions for high-value chemical production from carbon monoxide

open access: yesEngineering Biology, 2019
Clostridium autoethanogenum is an industrial microbe used for the commercial-scale production of ethanol from carbon monoxide. While significant progress has been made in the attempted diversification of this bioprocess, further improvements are ...
Rupert O.J. Norman   +13 more
doaj   +1 more source

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