Results 81 to 90 of about 2,952,613 (401)

Genome-scale CRISPRi screen identifies pcnB repression conferring improved physiology for overproduction of free fatty acids in Escherichia coli

Nature Communications
Microbial physiology plays a pivotal role in construction of superior microbial cell factories for efficient biosynthesis of desired products. Here we identify that pcnB repression confers improved physiology for overproduction of free fatty acids (FFAs)
Lixia Fang, Xueyan Hao, Jie Fan, Xiaolei Liu, Yaru Chen, Lian Wang, Xiaoying Huang, Hao Song, Yingxiu Cao   +8 more
doaj   +1 more source

Drop-in biofuel production using fatty acid photodecarboxylase from Chlorella variabilis in the oleaginous yeast Yarrowia lipolytica

Biotechnology for Biofuels, 2019
Background Oleaginous yeasts are potent hosts for the renewable production of lipids and harbor great potential for derived products, such as biofuels.
Stefan Bruder, Eva Johanna Moldenhauer, Robert Denis Lemke, Rodrigo Ledesma-Amaro, Johannes Kabisch   +4 more
doaj   +1 more source

Awareness of and Attitudes Toward Nanotechnology and Synthetic Biology [PDF]

, 2008
Based on a survey and focus groups, examines Americans' awareness of nanotechnology and synthetic biology, their initial impressions, and their assessments of the tradeoffs between the potential benefits and ...

core  

TinkerCell: Modular CAD Tool for Synthetic Biology [PDF]

, 2009
Synthetic biology brings together concepts and techniques from engineering and biology. In this field, computer-aided design (CAD) is necessary in order to bridge the gap between computational modeling and biological data. An application named TinkerCell
Bergmann, Frank T., Chandran, Deepak, Sauro, Herbert M.   +2 more
core   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion

Scientific Reports, 2021
Coiled-coil (CC) dimer-forming peptides are attractive designable modules for mediating protein association. Highly stable CCs are desired for biological activity regulation and assay.
Tjaša Plaper, Jana Aupič, Petra Dekleva, Fabio Lapenta, Mateja Manček Keber, Roman Jerala, Mojca Benčina   +6 more
doaj   +1 more source

A Molecular Implementation of the Least Mean Squares Estimator

, 2017
In order to function reliably, synthetic molecular circuits require mechanisms that allow them to adapt to environmental disturbances. Least mean squares (LMS) schemes, such as commonly encountered in signal processing and control, provide a powerful ...
Khammash, Mustafa, Zechner, Christoph
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Self-healing unmanned aerial vehicle skin for icing prevention and intelligent monitoring

npj Flexible Electronics
In-flight icing is a common hazard in unmanned aerial vehicles (UAVs), accounting for 25% of drone accidents due to their sensitivity to weight increase.
Sijia Xu, Ruiqi Li, Shu Tian, Junyu Yu, Chengtao An, Kai Yang, Jing Yang, Lei Zhang   +7 more
doaj   +1 more source

Application of combinatorial optimization strategies in synthetic biology

Nature Communications, 2020
In the first wave of synthetic biology, genetic elements, combined into simple circuits, are used to control individual cellular functions. In the second wave of synthetic biology, the simple circuits, combined into complex circuits, form systems-level ...
G. Naseri, M. Koffas
semanticscholar   +1 more source