Results 111 to 120 of about 13,423 (179)

Modulation of the endocannabinoid system reduces inflammatory signalling in canine mammary carcinoma cells

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Canine mammary carcinoma (CMC) is characterised by a chronic inflammatory microenvironment resembling human breast cancer; however, the upstream regulatory mechanisms driving this phenotype remain unclear. The endocannabinoid system (ECS) has emerged as a potential modulator of inflammation and tumour biology.
Gianluca Antonio Franco, Ylenia Marino, Claudia Rifici, Roberta Fusco, Davide di Paola, Salvatore Cuzzocrea, Giuseppe Catone, Cecilia Vullo, Enrico Gugliandolo   +8 more
wiley   +1 more source

Identification and Structural Elucidation of a New Synthetic Cannabinoid, MDMB-5'Br-PINACA, in Seized Herbal Materials. [PDF]

Drug Test Anal
de Godoi AB, Zeoly LA, Lanaro R, Oliveira IS, Diana MC, Yonamine M, Costa JL.   +6 more
europepmc   +1 more source

Effect of environmental temperature on oxidative status, inflammatory response and endocannabinoid system at oestrus in dairy cows

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Heat stress (HS) poses a significant challenge to dairy production under climate change, as it compromises fertility, productivity and overall health in cows. This seasonal observational cross‐sectional study investigated how environmental temperature affects oxidative status, inflammatory responses and endocannabinoid system (ECS ...
Alice Carbonari, Lorenza Frattina, Matteo Burgio, Vincenzo Cicirelli, Michal Andrzej Kosior, Alessandra Sfacteria, Bianca Gasparrini, Gabriele Marino, Roberta Verde, Fabiana Piscitelli, Annalisa Rizzo   +10 more
wiley   +1 more source

Entomological consequences and toxicological detection of synthetic cannabinoid receptor agonists (SCRAs) in necrophagous larvae (Diptera: Calliphoridae). [PDF]

Int J Legal Med
Blavier CAK, Villet MH, Zschiesche A, Auwärter V, Graw M, Geffert C, Groth OC.   +6 more
europepmc   +1 more source

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, Volume 121, Issue 6, Page 1530-1540, June 2026.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source

Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity. [PDF]

Forensic Toxicol
Alzu'bi A, Abu-El-Rub E, Almahasneh FA, Almazari R, Kasasbeh A, Ai-Jariri HF, Alrabie A, Al-Zoubi RM.   +7 more
europepmc   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, Volume 183, Issue 12, Page 3173-3194, June 2026.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

Intranasal naloxone to treat suspected synthetic cannabinoid overdose: A case report and literature review. [PDF]

Ment Health Clin
Dickinson J, Buckley T.
europepmc   +1 more source

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

Experimental Physiology, Volume 111, Issue 6, Page 2918-2944, 1 June 2026.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza, Marie Kempe, Sofia Grimmelsmann, Luiz Felipe Tavares, Ester Moreira De Castro‐Carletti, Angela Viegas Andrade, Liz Dennett, Harry Von Piekartz, Jorge Fuentes Contreras, Susan Armijo‐Olivo   +9 more
wiley   +1 more source

Computational-Assisted Development of Molecularly Imprinted Polymers for Synthetic Cannabinoid Recognition. [PDF]

ACS Omega
Carneiro LM, Gonçalves Araújo KR, Melo DU, Bartoloni FH, Soares AL, Yonamine M, Homem-de-Mello P.   +6 more
europepmc   +1 more source