Results 121 to 130 of about 13,423 (179)

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition

The Journal of Physiology, Volume 604, Issue 12, Page 4984-5010, 15 June 2026.
Abstract figure legend Postsynaptic depolarisation and increases in intracellular Ca2+ ([Ca2+]i) trigger the synthesis of endocannabinoids (eCBs), which are hypothesised to enhance tonic GABAergic inhibition via two primary pathways. In the proposed autocrine mechanism, eCBs activate postsynaptic somatodendritic or mitochondrial CB1 receptors ...
Roberto Colangeli, Fiorenzo Conti
wiley   +1 more source

Clinical Management of Synthetic-Cannabinoid-Induced Psychosis: A Systematic Review of Treatment Strategies and Outcomes. [PDF]

Brain Sci
Mosca A, Chiappini S, Miuli A, Cavallotto C, Pettorruso M, Martinotti G, Schifano F.   +6 more
europepmc   +1 more source

Structure-activity relationship of prevalent synthetic cannabinoid metabolites on hCB₁ in vitro and in silico dynamics. [PDF]

Acta Pharmacol Sin
Åstrand A, Laudadio E, Gameli PS, Martin L, Carlier J, Busardò FP, Dahlén J, Wu X, Konradsson P, Vikingsson S, Kronstrand R, Gréen H.   +11 more
europepmc   +1 more source

The Synthetic Cannabinoid ADB-FUBINACA Disrupts Mitochondrial Morphology and Dynamics during Neuronal Differentiation of NG108-15 Cells. [PDF]

Mol Neurobiol
Malheiro RF, Costa AC, Pereira-Teixeira C, Carmo H, Carvalho F, Silva JP.   +5 more
europepmc   +1 more source

Exacerbated cardiac dysfunction from combined alcohol binge and synthetic cannabinoid use. [PDF]

Biomed Pharmacother
Paloczi J, Gunduz-Cinar O, Yokus B, Paes-Leme B, Haskó G, Kunos G, Holmes A, Pacher P.   +7 more
europepmc   +1 more source

An Outbreak of Synthetic Cannabinoid-Adulterated Tianeptine Products in New Jersey - Case Series. [PDF]

J Med Toxicol
Counts CJ, Spadaro AV, Cerbini TA, Krotulski AJ, Walton SE, Greller HA, Nelson LS, Ruck BE, Hung O, Logan B, Calello DP.   +10 more
europepmc   +1 more source

Synthetic cannabinoid use among noninstitutionalized individuals in the United States, 2021-2023. [PDF]

Drug Alcohol Depend
Palamar JJ, Abukahok N, Le A.
europepmc   +1 more source

Synthetic Cannabinoid (Mojo)-Induced ST-Segment Elevation Myocardial Infarction: A Case Report. [PDF]

Cureus
Udoh KE, Udoh KE, Udoh AE.
europepmc   +1 more source

Acute and subacute cardiovascular effects of synthetic cannabinoid JWH-018 in rat. [PDF]

Forensic Toxicol
Ozhan O, Ermis N, Celbis O, Samdanci E, Petekkaya S, Oruc M, Soylu O, Koparir P, Acet A, Parlakpinar H.   +9 more
europepmc   +1 more source

Characterization of the Behavioral and Molecular Effects of Acute Exposure to the Fourth-Generation Synthetic Cannabinoid, 5F-EDMB-PICA, in Male Mice of Different Age Groups. [PDF]

Int J Mol Sci
Li K, Xu P, Wang Y, Shi X, Chen Y, Zhang S, Ran J, Qiao Y, Xu Y, Pang Y, Di B.   +10 more
europepmc   +1 more source