Results 21 to 30 of about 1,044,094 (254)

Synthetic cannabinoids in the kidneys [PDF]

Revista da Associação Médica Brasileira, 2017
Acute kidney injury is an important cause of mortality and morbidity today and can occur due to several reasons. As time, geographic regions, and living conditions change, various etiological agents arise with nephrotoxic effects. Awareness of such nephrotoxic effects has been raised with the increasing frequency of addictive substance use, especially ...
Alp, Alper, Akdam, Hakan, Avcıoğlu, Banu Yılmaz, Ersan, Sibel   +3 more
openaire   +3 more sources

Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells [PDF]

PeerJ, 2019
Background Synthetic cannabinoids are a commonly used class of recreational drugs that can have significant adverse effects. There have been sporadic reports of co-consumption of illicit drugs with rodenticides such as warfarin and brodifacoum (BFC) over
Shivani Sachdev, Rochelle Boyd, Natasha L. Grimsey, Marina Santiago, Mark Connor   +4 more
doaj   +2 more sources

Synthesis of nine potential synthetic cannabinoid metabolites with a 5F-4OH pentyl side chain from a scalable key intermediate

, 2021
Synthetic cannabinoid metabolites with a 5F-4OH pentyl side chain are of great interest, and several synthetic methods have been developed for the synthesis of these types of metabolites in the literature, which is either lengthy or inappropriate for ...
Konradsson, Peter,, Dahlén, Johan,, Wu, Xiongyu,, Wallgren, Jakob,, Bopp, Daniel,   +4 more
core   +1 more source

The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system [PDF]

, 2008
INTRODUCTION: Ghrelin and cannabinoids stimulate appetite, this effect possibly being mediated by the activation of hypothalamic AMP-activated protein kinase (AMPK), a key enzyme in appetite and metabolism regulation. The cannabinoid receptor type 1 (CB1)
Judith Harvey-White, Francesca Lolli, Farkas, I., Amin, F., Mirjam Christ-Crain, Kola, Blerina, Fekete, Csaba, George Kunos, Kola, B., Faisal Amin, A. B. Grossman, M. Korbonits, Blerina Kola, Liposits, Zsolt, G. Kunos, Ashley B Grossman, B. Kola, Amin, F, Gábor Wittmann, Kunos, George, Christ-Crain, M, Farkas, Imre, Lolli, F, Zsolt Liposits, Lolli, F., F. Amin, Farkas, I, Christ-Crain, M., Korbonits, M., I. Farkas, Grossman, AB, C. Fekete, Kola, B, Harvey-White, J., Wittmann, Gábor, Korbonits, Márta, G. Wittmann, Harvey-White, J, Fekete, C, Harvey-White, Judith, Márta Korbonits, Imre Farkas, Liposits, Z, Z. Liposits, Grossman, Ashley B., Ashley B. Grossman, Wittmann, G., Christ-Crain, Mirjam, Amin, Faisal, Lolli, Francesca, Liposits, Z., M. Christ Crain, J. Harvey White, Fekete, C., Korbonits, M, Kunos, G., Csaba Fekete, Grossman, A. B., Kunos, G, Wittmann, G   +59 more
core   +3 more sources

Craving among Synthetic Cannabinoid Users: A Qualitative Approach

Addicta: The Turkish Journal on Addictions, 2021
Synthetic cannabinoids are accepted as new-design substances with strong addictive properties. The development of addiction in users is linked to craving.
Yağmur Suadiye Dalgıç, Hakan Coşkunol   +1 more
doaj   +1 more source

Weber Syndrome secondary to synthetic cannabinoid use

, 2021
Synthetic cannabinoid abuse may lead to physical and psychological disorders. This substance has disseminated rapidly in recent years and the literature about its bad consequences is rather sparse.
Yargic, Lutfi Ilhan, Karabulut, Sercan
core   +1 more source

Cannabinoids for the control of experimental multiple sclerosis [PDF]

, 2010
PhDThere have been numerous studies reporting that cannabinoids, both exogenous and endogenous, have a potential beneficial function during incidences of neurological damage.
Pryce, Gareth
core   +2 more sources

Synthetic cannabinoids

Northern Clinics of Istanbul, 2014
Use of cannabinoids is increasing at an alarming rate. Their easy availability, cheapness, perceptive legality and difficulty in detecting its presence with standard urine toxicologic tests, and similar factors probably contribute to the increased use, and popularity of synthetic cannabinoids. Although laws, and regulations concerning auditing of these
openaire   +3 more sources

Novel putative ligands of cannabinoid receptors: synthesis and effects on cell signaling and neuronal functions [PDF]

The Ukrainian Biochemical Journal, 2023
Cannabinoid ligands are known to possess neuroprotective actions and may have utility in the treatment of neurodegeneration. The major targets for cannabinoids include the classical CB1 cannabinoid receptor, as well as the novel cannabinoid receptor ...
J. Senkiv, A. Kryshchyshyn-Dylevych, D. Khylyuk, M. Wujec, R. Stoika, A. J. Irving, R. Lesyk   +6 more
doaj   +1 more source

The Modulating Role of Sex and Anabolic-Androgenic Steroid Hormones in Cannabinoid Sensitivity

Frontiers in Behavioral Neuroscience, 2018
Cannabis is the most commonly used illicit drug worldwide. Although its use is associated with multiple adverse health effects, including the risk of developing addiction, recreational and medical cannabis use is being increasing legalized.
Dicky Struik, Fabrizio Sanna, Liana Fattore   +2 more
doaj   +1 more source