Results 111 to 120 of about 1,032,308 (279)

The Psychopharmacology of Novel Synthetic Cannabinoids [PDF]

open access: yes, 2017
Over recent years, the rapid proliferation of novel psychoactive substances has presented significant challenges to health professionals, regulators, and forensic scientists alike.
Kevin, Richard Charles
core  

Synthetic cannabinoids: the hidden side of Spice drugs

open access: yes, 2017
Spice drugs are herbal mixtures sprayed with synthetic cannabinoids designed to mimic the psychoactive ingredient in marijuana [Δ9-tetrahydrocannabinol (Δ9-THC)] and synthesized by introducing modifications to the chemical structure of parental compounds
Pintori N.   +5 more
core   +1 more source

Methylenedioxymethamphetamine (MDMA)‐related fatal poisoning in Australia, 2016 to 2025: Trends, characteristics and toxicology

open access: yesAddiction, EarlyView.
Abstract Aims To determine: (1) Population rates of fatal methylenedioxymethamphetamine (MDMA)‐related poisoning over the period 2016–2023, years with high closure rates in the National Coronial Information System (NDIS); (2) the case characteristics of known cases of fatal MDMA‐related poisoning, 2016–2025; and (3) whether there have been changes in ...
Shane Darke   +5 more
wiley   +1 more source

Cryptogenic stroke in young patients and cannabis use: case presentation and literature review

open access: yesNeurologijos seminarai, 2019
Approximately 10% of ischemic strokes occur in people under the age of 50 – this is called early on set or stroke in young adults. In this patient population, there is an especially high number of cryptogenic strokes, where etiology is not identified or
A. Atkočiūnas   +4 more
doaj   +1 more source

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr   +10 more
wiley   +1 more source

Further consideration of the synthetic cannabinoids. [PDF]

open access: yes, 2012
Report from the ACMD to the UK Home Secretary regarding synthetic cannabinoids. In July 2009 the Advisory Council on the Misuse of Drugs (ACMD) provided advice on harmful synthetic compounds (synthetic cannabinoid receptor agonists).

core  

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

The strength of your cannabinoid may be higher than you think. Synthetic Cannabinoids (‘Spice’). [PDF]

open access: yes, 2017
Synthetic cannabinoids can mimic the effects of cannabis and can cause extreme agitation and ...

core  

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Life-threatening constrictive pericarditis accompanied by synthetic cannabinoid use: A case report and literature review

open access: yesJournal of Acute Disease
Rationale: Synthetic cannabinoids are increasingly used as recreational drugs and have been associated with adverse cardiovascular effects. However, reports of synthetic cannabinoids accompanied by constrictive pericarditis are limited. Patient’s concern:
Mahsa Behnemoon   +4 more
doaj   +1 more source

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