Results 121 to 130 of about 14,173 (257)

Management of Rodenticide Poisoning Associated with Synthetic Cannabinoids.

, 2019
Synthetic cannabinoids may be adulterated with potent vitamin K antagonists, which should be considered if a patient presents with unexplained coagulopathy, widespread bleeding, and a history of synthetic cannabinoid use.
Kevin Kolman (12523891), Jaimmie D Bhagat (12523888), Sarah Unterman (12523885), Patrick Godwin (10637534), Zane Elfessi (10641362)   +4 more
core   +1 more source

Delta‐9‐Tetrahydrocannabinol (THC) Before Bedtime: Feasibility and Mechanistic Pilot Study on Sleep and Cardiac Autonomic Activity

Journal of Sleep Research, EarlyView.
ABSTRACT Disordered sleep is a common reason individuals report using cannabis, yet the physiological effects of Δ9‐tetrahydrocannabinol (Δ9‐THC) on sleep and autonomic regulation remain incompletely understood. Early studies reported acute sleep‐promoting effects of Δ9‐THC, but chronic use has been associated with disrupted sleep and possible ...
Joshua E. Gonzalez, Alicia V. Stewart, Jacquelin L. Ellison, Omar H. Ordaz, LaTroy D. Robinson, Noal A. Clemons, Jonathan S. Emens, Sean P. M. Rice, Steven A. Shea, Nicole P. Bowles   +9 more
wiley   +1 more source

Potential Implications of Multi-Drug Exposure with Synthetic Cannabinoids: A Scoping Review of Human Case Studies

Psychoactives
Synthetic cannabinoids are a rapidly evolving, diverse class of new psychoactive substances. Synthetic cannabinoid use results in a higher likelihood of adverse events and hospitalization when compared to cannabis use.
Lucy R. Thomsen, Rhonda J. Rosengren, Michelle Glass   +2 more
doaj   +1 more source

Synthetic cannabinoids: characteristics, use and clinical implications

, 2017
Synthetic cannabinoids are chemicals that bind to cannabinoid receptors and produce effects similar to those of tetrahydrocannabinol. Although initially designed as possible pharmacological tools, they are currently one of the most important of the so ...
EMILIO SANCHEZ HERVAS
core   +1 more source

Biotransformation of monoterpenols upon pre‐treatment with oregano essential oil vapour alleviates downy mildew susceptibility in grapevine leaves

Plant Biology, EarlyView.
Pre‐treatment of grapevine plants with oregano essential oil vapour alleviates downy mildew susceptibility by accumulation of monoterpenol glycosides. Abstract Grapevine downy mildew, caused by the oomycete Plasmopara viticola, is a destructive disease that causes major economic losses as most elite grapevine cultivars are susceptible to this pathogen.
J. R. P. E. Mars, R. M. de Graaf, R. S. Jansen, S. Coolen, P. H. J. Kouwer, J. L. Peters, R. A. Anaia   +6 more
wiley   +1 more source

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition

The Journal of Physiology, EarlyView.
Abstract figure legend Postsynaptic depolarisation and increases in intracellular Ca2+ ([Ca2+]i) trigger the synthesis of endocannabinoids (eCBs), which are hypothesised to enhance tonic GABAergic inhibition via two primary pathways. In the proposed autocrine mechanism, eCBs activate postsynaptic somatodendritic or mitochondrial CB1 receptors ...
Roberto Colangeli, Fiorenzo Conti
wiley   +1 more source

Synthetic cannabinoids: the hidden side of Spice drugs

, 2017
Spice drugs are herbal mixtures sprayed with synthetic cannabinoids designed to mimic the psychoactive ingredient in marijuana [Δ9-tetrahydrocannabinol (Δ9-THC)] and synthesized by introducing modifications to the chemical structure of parental compounds
Pintori N., Barbara Loi, Maddalena Mereu, Loi B., Mereu M., Nicholas Pintori   +5 more
core   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Management of emergencies related to cannabis, its derivatives, and synthetic cannabinoids: an update

Debates em Psiquiatria
Introduction: Cannabis use and the availability of high-potency cannabis-derived products and synthetic cannabinoids have increased worldwide, contributing to a growing burden of emergency presentations involving intoxication, agitation, psychosis ...
Leonardo Baldaçara, Gislene Alves da Rocha, Roberto Mendes dos Santos, Elie Leal de Barros Calfat, Quirino Cordeiro, Alexandrina Maria Augusto da Silva Meleiro, Lucas Alves Pereira   +6 more
doaj   +1 more source

Further consideration of the synthetic cannabinoids.

, 2012
Report from the ACMD to the UK Home Secretary regarding synthetic cannabinoids. In July 2009 the Advisory Council on the Misuse of Drugs (ACMD) provided advice on harmful synthetic compounds (synthetic cannabinoid receptor agonists).

core