Results 131 to 140 of about 1,032,308 (279)

University students’ attributions for abstinence from synthetic cannabinoids and synthetic cathinones

open access: yes, 2018
Background: Synthetic cannabinoids and synthetic cathinones are two increasingly available and potentially dangerous classes of substances. Objective: We designed this study to test whether university students rated the influence of different types of ...
Jon E. Sprague (3817819)   +2 more
core   +1 more source

The fight of innate immunity and abnormal cannabinoids against Candida infection

open access: yesBritish Journal of Pharmacology, EarlyView.
Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori   +2 more
wiley   +1 more source

Potential Implications of Multi-Drug Exposure with Synthetic Cannabinoids: A Scoping Review of Human Case Studies

open access: yesPsychoactives
Synthetic cannabinoids are a rapidly evolving, diverse class of new psychoactive substances. Synthetic cannabinoid use results in a higher likelihood of adverse events and hospitalization when compared to cannabis use.
Lucy R. Thomsen   +2 more
doaj   +1 more source

GLP‐1 receptor activation attenuates chronic migraine‐like behaviour: Sex‐specific modulation of opioid‐ and endocannabinoid‐related pathways

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Chronic migraine (CM) is a highly disabling condition that remains suboptimally treated. Metabolic disturbances may trigger migraine chronification, whereas impaired endogenous pain inhibition contributes to CM development. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), used for type 2 diabetes and obesity, show efficacy ...
Katarina Sićović   +6 more
wiley   +1 more source

Hijacking of Basic Research: The Case of Synthetic Cannabinoids

open access: yes, 2011
Gathering and communicating knowledge are important aspects of the scientific endeavor. Yet presentation of data in public forums such as scientific meetings and publications makes it available not only to scientists, but also to others who may have ...
Brian Thomas   +4 more
core   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

open access: yesThe FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki   +7 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

open access: yesThe FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén   +11 more
wiley   +1 more source

Synthetic cannabinoids intoxication cases in Italy: analytical identification and clinical findings

open access: yes, 2012
Description of synthetic cannabinoids intoxication cases registered in Italy by the National Early Warning System ...
C. Rimondo   +14 more
core   +1 more source

Management of emergencies related to cannabis, its derivatives, and synthetic cannabinoids: an update

open access: yesDebates em Psiquiatria
Introduction: Cannabis use and the availability of high-potency cannabis-derived products and synthetic cannabinoids have increased worldwide, contributing to a growing burden of emergency presentations involving intoxication, agitation, psychosis ...
Leonardo Baldaçara   +6 more
doaj   +1 more source

Semi-synthetic cannabinoids remain a potent concern in Ireland.

open access: yes
Letter to the Editor. Cannabis-like drugs known as “semi-synthetic cannabinoids” (SSCs) and other substitutes continue to be sold commercially throughout Ireland despite recent law changes that attempted to prohibit their sale.
Bond, Ben, Cannon, Mary
core   +1 more source

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