Results 131 to 140 of about 11,438 (231)

Exploring the Impact of Chirality of Synthetic Cannabinoids and Cathinones: A Systematic Review on Enantioresolution Methods and Enantioselectivity Studies. [PDF]

Int J Mol Sci
Almeida AS, Santos RMG, Guedes de Pinho P, Remião F, Fernandes C.   +4 more
europepmc   +1 more source

Neuroprotective Effects of Biosynthetic d‐Calcium Pantothenate and Cyanocobalamin Against MPTP‐Induced Parkinsonism via Microbiota Modulation, Metabolic Homeostasis Restoration, and Endoplasmic Reticulum Stress Inhibition

Food Frontiers, Volume 7, Issue 4, July 2026.
Biosynthetic D‐calcium pantothenate and cyanocobalamin alleviate MPTP‐induced Parkinsonism in mice by modulating gut microbiota, restoring metabolic homeostasis, and inhibiting Endoplasmic Reticulum Stress. ABSTRACT Vitamin B5 (VB5) and Vitamin B12 (VB12) are essential micronutrients widely distributed in functional foods, yet their neuroprotective ...
Yaru Chen, Shaohui Zhu, Yajie Ruan, Kaiqi Zheng, Jing Wang, Qianqian Guan, Tao Xiong   +6 more
wiley   +1 more source

Serum zonulin, brain-derived neurotrophic factor, and oxidative stress levels in individuals using paper (A4) impregnated with synthetic cannabinoids. [PDF]

Front Psychiatry
Kulaksızoğlu S, Erdoğan A, Tosun O, Görgülü ZY, Acar E, Kireç Y, Karabulut S, Kulaksızoğlu B, Cinemre B, Metin Ö.   +9 more
europepmc   +1 more source

Synthetic Cannabinoids-Related Cardiovascular Emergencies: A Review of the Literature. [PDF]

Cureus, 2023
Hasan MR, Tabassum T, Tabassum T, Tanbir MA, Abdelsalam M, Nambiar R.   +5 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Abuse of Synthetic Cannabinoids and Cathinones in a Patient on Buprenorphine-Naloxone Treatment: A Case Report. [PDF]

Cureus, 2023
Awasthi H.
europepmc   +1 more source

Advances in pharmacotherapy for vascular cognitive impairment and vascular dementia: An update of 2025

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.
Abstract Vascular cognitive impairment (VCI), including vascular dementia (VaD), encompasses a spectrum of cognitive deficits resulting from cerebrovascular pathology, ranging from mild impairment to dementia. As the second leading cause of dementia worldwide, VCI remains a major therapeutic challenge.
Doan‐Khanh Tran, Yi‐Chun Kuan, Li‐Kai Huang, Chaur‐Jong Hu   +3 more
wiley   +1 more source

Study on Phase I Metabolic Processes and Metabolite Biomarker Identification of Synthetic Cannabinoids 5F-ADB-PINACA and 5F-ADBICA in Human Liver Microsomes and Zebrafish Model. [PDF]

Molecules
Li H, Zheng H, Zhong S, Zhao Y, Lin J, Su H, Qian Z, Wang Y.   +7 more
europepmc   +1 more source

Toxicity of Synthetic Cannabinoids in K2/Spice: A Systematic Review. [PDF]

Brain Sci, 2023
de Oliveira MC, Vides MC, Lassi DLS, Torales J, Ventriglio A, Bombana HS, Leyton V, Périco CA, Negrão AB, Malbergier A, Castaldelli-Maia JM.   +10 more
europepmc   +1 more source

Abuse Potential and Neurotoxic Effects of the Synthetic Cannabinoid 4F‐ABUTINACA Self‐Administration in Adult Male Rats

Addiction Biology, Volume 31, Issue 7, July 2026.
4F ABUTINACA maintains stable intravenous self‐administration at low doses in male rats, supporting its high abuse potential. Chronic exposure to 4F‐ABUTINACA induces persistent anxiety‐like behaviors and is associated with region‐specific neurotoxicity in the hippocampus, prefrontal cortex and nucleus accumbens, alongside dysregulation of the BDNF ...
Baobao Shi, Huizhen Liu, Manqing Wu, Yuting Wang, Dan Fu, Lili Wen, Huifen Liu, Peng Xu, Wenhua Zhou, Haitao Wang, Miaojun Lai   +10 more
wiley   +1 more source