Results 151 to 160 of about 14,173 (257)

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Rapid LC-QTOF-MS screening method for semi-synthetic cannabinoids in whole blood. [PDF]

J Anal Toxicol
Schirmer W, Walton SE, Weinmann W, Schürch S, Logan BK, Krotulski AJ.   +5 more
europepmc   +1 more source

A Feasibility Assessment of the FDA Adverse Event Reporting System for the Detection of Cannabis‐Related Safety Signals

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Background The applicability of spontaneous reporting systems such as the US Food and Drug Administration Adverse Event Reporting System (FAERS) to detect cannabis‐related safety signals remains unclear due to the potential for discrepant reporting patterns between pharmaceutical and non‐pharmaceutical cannabis‐derived products (CDPs ...
Priscilla O. M. V. Lopes, Cory S. Harris, Christopher A. Gravel   +2 more
wiley   +1 more source

Synthetic cannabinoids in human post-mortem samples - ADB-BUTINACA and metabolites in three fatalities. [PDF]

Front Toxicol
Zschiesche A, Köpfler S, Wunder C, Keiler AM, Görg J, Walz CP, Fliss B, Germerott T, Auwärter V, Huppertz LM.   +9 more
europepmc   +1 more source

AB‐MDMSBA—Not a Synthetic Cannabinoid Receptor Agonist

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study uses classical in vitro pharmacology approaches to establish that AB‐MDMSBA does not bind to or activate the cannabinoid CB1 receptor and therefore should not be classified as a synthetic cannabinoid receptor agonist. ABSTRACT Synthetic cannabinoids remain one of the most prominent classes of New Psychoactive Substances (NPS).
Monica Patel, Dharshini Ganeshan, Izzy Horgan, Hannah Partington, Michelle Glass   +4 more
wiley   +1 more source

Modulation of the endocannabinoid system reduces inflammatory signalling in canine mammary carcinoma cells

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Canine mammary carcinoma (CMC) is characterised by a chronic inflammatory microenvironment resembling human breast cancer; however, the upstream regulatory mechanisms driving this phenotype remain unclear. The endocannabinoid system (ECS) has emerged as a potential modulator of inflammation and tumour biology.
Gianluca Antonio Franco, Ylenia Marino, Claudia Rifici, Roberta Fusco, Davide di Paola, Salvatore Cuzzocrea, Giuseppe Catone, Cecilia Vullo, Enrico Gugliandolo   +8 more
wiley   +1 more source

Synthetic Cannabinoids: Law vs. Science

, 2014
Synthetic cannabinoids are designer drugs which have been made to mimic the effects experiences by tetra-hydro-cannabinol (THC). These substances are sprayed on herbal blends and ingested through smoking.
Sterling, Melissa R.
core  

Effect of environmental temperature on oxidative status, inflammatory response and endocannabinoid system at oestrus in dairy cows

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Heat stress (HS) poses a significant challenge to dairy production under climate change, as it compromises fertility, productivity and overall health in cows. This seasonal observational cross‐sectional study investigated how environmental temperature affects oxidative status, inflammatory responses and endocannabinoid system (ECS ...
Alice Carbonari, Lorenza Frattina, Matteo Burgio, Vincenzo Cicirelli, Michal Andrzej Kosior, Alessandra Sfacteria, Bianca Gasparrini, Gabriele Marino, Roberta Verde, Fabiana Piscitelli, Annalisa Rizzo   +10 more
wiley   +1 more source

Data Hidden in Sewage: Advanced Methods for Identification and Quantification of Synthetic Cannabinoids in Urban Wastewater. [PDF]

Molecules
Kurzeja W, Kuczer M, Matysiak J, Klupczyńska-Gabryszak A.   +3 more
europepmc   +1 more source

Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada

Addiction, Volume 121, Issue 6, Page 1530-1540, June 2026.
Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie, Ria Garg, Pamela Leece, Gillian Kolla, Elaine Hyshka, Mina Tadrous, Tara Gomes   +6 more
wiley   +1 more source