Vitamin D is an essential fat‐soluble nutrient primarily obtained through cutaneous synthesis triggered by ultraviolet exposure and dietary intake. After systemic metabolism and activation, it binds to vitamin D receptors widely distributed in the central and peripheral nervous systems, exerting pleiotropic neuroprotective and regulatory biological ...
Nan Zhao +4 more
wiley +1 more source
Serum zonulin, brain-derived neurotrophic factor, and oxidative stress levels in individuals using paper (A4) impregnated with synthetic cannabinoids. [PDF]
Kulaksızoğlu S +9 more
europepmc +1 more source
Vaporised etomidate (“space oil”) misuse: A narrative review
Abstract Background Etomidate, a well‐established intravenous induction agent valued for haemodynamic stability, has emerged as a recreational drug via e‐cigarette vaping (“space oil”), particularly in Asia, including Hong Kong, prompting regulatory controls amid rising emergency presentations.
Sui Wa Au, Yu‐Yeung Yip
wiley +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
NMR Spectroscopic Reference Data of Synthetic Cannabinoids Sold on the Internet. [PDF]
Hubner EM +5 more
europepmc +1 more source
Abstract Cannabis‐based medicinal products (CBMPs) are increasingly prescribed for chronic pain, yet the supporting evidence remains limited and the extent to which patients differ in their response is poorly understood. This study applied longitudinal k‐means clustering to pain‐severity trajectories in patients treated with CBMPs for chronic pain to ...
Simon Erridge +11 more
wiley +1 more source
Microgels of Levan Polysaccharide and Their Use for the Controlled Release of CBD
The levan hydrogels as a CBD drug delivery system were studied in six matters. The swelling behavior was investigated regarding pH and temperature dependency. Morphological and rheological analysis showed that syringe‐injected hydrogels provide an effective surface area by keeping the mechanical properties of the bulk hydrogel.
Ece Özyağcı +6 more
wiley +1 more source
Study on Phase I Metabolic Processes and Metabolite Biomarker Identification of Synthetic Cannabinoids 5F-ADB-PINACA and 5F-ADBICA in Human Liver Microsomes and Zebrafish Model. [PDF]
Li H +7 more
europepmc +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Systematic Characterization of In Vitro and In Vivo Metabolic Pathways and Identification of Novel Biomarkers of 26 Synthetic Cannabinoids. [PDF]
Ning Y +10 more
europepmc +1 more source

