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Toxicology of synthetic cannabinoids
Annales de Biologie CliniqueSynthetic cannabinoids (CS), or synthetic endocannabinoid receptor agonists, were initially synthesized for basic research into exocannabinoid signaling pathways, as well as in clinical research for their analgesic properties. The use of CS for recreational purposes is a recent phenomenon, but one that has grown very quickly in recent years, since ...
Youssef, Mouraouakkil +5 more
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Synthetic cannabinoids revealing adrenoleukodystrophy
Journal of Clinical Neuroscience, 2016We report a 41-year-old man who presented with a first generalized tonic-clonic seizure after recent consumption of a synthetic cannabinoid. MRI showed extensive bilateral, mainly frontal, white matter lesions. Blood analysis for very long chain fatty acids was compatible with adrenoleukodystrophy, and a missense mutation in the ABCD1 gene confirmed ...
Avi, Fellner +2 more
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Sentetik kannabinoidler SK , kannabinollerin bir alt grubu olup, son yıllarda uyuşturucu kullanımında çok ön planda yer almaya başlamıştır. Bu maddelerin kullanımı günümüzde özellikle gençlerde ve genç erişkinlerde artmaktadır. Hem zehirlenmeler nedeni ile Acil servislere başvuran olgular her geçen gün artmakta, hem de ölümle sonuçlanan olgular ...
PAKİŞ, Işıl, POLAT, Oğuz
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PAKİŞ, Işıl, POLAT, Oğuz
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Journal of Psychiatric Practice, 2012
In the past few years, synthetic cannabinoid products have been increasingly used by adolescents and young adults. These products are marketed as herbal or aromatic incense and potpourri, but their psychoactive properties appear to be due to the addition of synthetic cannabinoids.
Daniel, Castellanos, Gabriel, Thornton
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In the past few years, synthetic cannabinoid products have been increasingly used by adolescents and young adults. These products are marketed as herbal or aromatic incense and potpourri, but their psychoactive properties appear to be due to the addition of synthetic cannabinoids.
Daniel, Castellanos, Gabriel, Thornton
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Blood concentrations of synthetic cannabinoids
Clinical Toxicology, 2020Synthetic cannabinoids (SCs) are the largest and most diverse group of new psychoactive substances. Their influence on organism is unpredictable and often lead to intoxications, including fatal poisonings. The interpretation of blood concentrations of detected SC although complicated, can help to determine the effects of an administered drug.
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The emergence and analysis of synthetic cannabinoids
Drug Testing and Analysis, 2011AbstractIn late 2008, several synthetic cannabinoids were detected in herbal smoking mixtures. Typical of these products were ‘Spice Gold’, ‘Spice Silver’ and ‘Yucatan Fire’, but many other products have since appeared. The analytes detected, such as JWH‐018 and CP47,497 are experimental compounds, some of which were never designed for human use.Both ...
Simon, Hudson, John, Ramsey
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Interpersonal violence and synthetic cannabinoids
British Journal of Oral and Maxillofacial Surgery, 2017The medicinal benefits of cannabis have led to the develpment of synthetic cannabinoid receptor agonists, for the alliation of cancer and other conditions.1 Unfortunately, llicit manufacturers have commandeered their production or recreational use. Known colloquially as “spice”, or by ther pseudonyms, these substances have garnered attention n the ...
Alexander J, Rickart +2 more
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The Synthetic Cannabinoid Withdrawal Syndrome
Journal of Addiction Medicine, 2013Little is known about the effects of synthetic cannabinoids. There has been only one previous report of a withdrawal syndrome from synthetic cannabinoids. We report two cases of a withdrawal syndrome from prolonged habitual use of synthetic cannabinoids.Withdrawal from delta-9-THC has been described as a syndrome of anxiety, myalgias, chills, and ...
Nicholas, Nacca +5 more
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Metabolism of classical cannabinoids and the synthetic cannabinoid JWH‐018
Clinical Pharmacology & Therapeutics, 2015Although the putative pharmacological targets of synthetic cannabinoids (SCBs) abused in “K2” and “Spice” are similar to Δ9‐tetrahydrocannabinol (Δ9‐THC), it remains unclear why SCB toxicity is similar yet different from marijuana. There are obvious potency and efficacy differences, but also important metabolic differences that help explain the unique ...
M K, Su +3 more
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