Results 211 to 220 of about 14,173 (257)
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Focus on cannabinoids and synthetic cannabinoids
Clinical Pharmacology & Therapeutics, 2016The recent emergence of a multitude of synthetic cannabinoids (SCs) has generated a wealth of new information, suggesting the usefulness of state‐of‐the‐art on lato sensu cannabinoids. By modulating a plurality of neurotransmission pathways, the endocannabinoid system is involved in many physiological processes that are increasingly explored.
R, Le Boisselier +3 more
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Psychosis and synthetic cannabinoids
Psychiatry Research, 2018Synthetic cannabinoid (SC) products have gained popularity as abused drugs over the past decade in many countries. The SCs broadly impact psychological state (e.g., mood, suicidal thoughts and psychosis) and physiological functions (e.g., cardiovascular, gastrointestinal and urinary).
Huiqiong Deng +3 more
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Synthetic cannabinoids: Analysis and metabolites
Life Sciences, 2014Cannabimimetics (commonly referred to as synthetic cannabinoids), a group of compounds encompassing a wide range of chemical structures, have been developed by scientists with the hope of achieving selectivity toward one or the other of the cannabinoid receptors CB1 and CB2.
Mahmoud A Elsohly +2 more
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2023
New synthetic cannabinoid agonists have been synthesized during the last decades and promoted for their psychoactive effects, mimicking those of delta-9-tetrahydrocannabinol. These newest cannabimimetic drugs show binding affinities for the cannabinoid CB1 and/or the CB2 receptors.
Fattore, Liana, Marti, Matteo
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New synthetic cannabinoid agonists have been synthesized during the last decades and promoted for their psychoactive effects, mimicking those of delta-9-tetrahydrocannabinol. These newest cannabimimetic drugs show binding affinities for the cannabinoid CB1 and/or the CB2 receptors.
Fattore, Liana, Marti, Matteo
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Toxicology of synthetic cannabinoids
Annales de Biologie CliniqueSynthetic cannabinoids (CS), or synthetic endocannabinoid receptor agonists, were initially synthesized for basic research into exocannabinoid signaling pathways, as well as in clinical research for their analgesic properties. The use of CS for recreational purposes is a recent phenomenon, but one that has grown very quickly in recent years, since ...
Youssef, Mouraouakkil +5 more
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Nonpsychotropic Synthetic Cannabinoids
Current Pharmaceutical Design, 2000Unlike natural cannabinoids which belong to the 6aR - trans series, the synthetic dexanabinol (HU-211), a 6aS-trans enantiomer, does not have affinity toward cannabinoid receptors and is devoid of cannabimimetic activity. On the other hand, dexanabinol demonstrated significant neuroprotective properties which prompted its development as a therapeutic ...
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Synthetic cannabinoids revealing adrenoleukodystrophy
Journal of Clinical Neuroscience, 2016We report a 41-year-old man who presented with a first generalized tonic-clonic seizure after recent consumption of a synthetic cannabinoid. MRI showed extensive bilateral, mainly frontal, white matter lesions. Blood analysis for very long chain fatty acids was compatible with adrenoleukodystrophy, and a missense mutation in the ABCD1 gene confirmed ...
Avi, Fellner +2 more
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Sentetik kannabinoidler SK , kannabinollerin bir alt grubu olup, son yıllarda uyuşturucu kullanımında çok ön planda yer almaya başlamıştır. Bu maddelerin kullanımı günümüzde özellikle gençlerde ve genç erişkinlerde artmaktadır. Hem zehirlenmeler nedeni ile Acil servislere başvuran olgular her geçen gün artmakta, hem de ölümle sonuçlanan olgular ...
PAKİŞ, Işıl, POLAT, Oğuz
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PAKİŞ, Işıl, POLAT, Oğuz
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Interpersonal violence and synthetic cannabinoids
British Journal of Oral and Maxillofacial Surgery, 2017The medicinal benefits of cannabis have led to the develpment of synthetic cannabinoid receptor agonists, for the alliation of cancer and other conditions.1 Unfortunately, llicit manufacturers have commandeered their production or recreational use. Known colloquially as “spice”, or by ther pseudonyms, these substances have garnered attention n the ...
Alexander J, Rickart +2 more
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Blood concentrations of synthetic cannabinoids
Clinical Toxicology, 2020Synthetic cannabinoids (SCs) are the largest and most diverse group of new psychoactive substances. Their influence on organism is unpredictable and often lead to intoxications, including fatal poisonings. The interpretation of blood concentrations of detected SC although complicated, can help to determine the effects of an administered drug.
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