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Journal of Psychiatric Practice, 2012
In the past few years, synthetic cannabinoid products have been increasingly used by adolescents and young adults. These products are marketed as herbal or aromatic incense and potpourri, but their psychoactive properties appear to be due to the addition of synthetic cannabinoids.
Daniel, Castellanos, Gabriel, Thornton
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In the past few years, synthetic cannabinoid products have been increasingly used by adolescents and young adults. These products are marketed as herbal or aromatic incense and potpourri, but their psychoactive properties appear to be due to the addition of synthetic cannabinoids.
Daniel, Castellanos, Gabriel, Thornton
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The emergence and analysis of synthetic cannabinoids
Drug Testing and Analysis, 2011AbstractIn late 2008, several synthetic cannabinoids were detected in herbal smoking mixtures. Typical of these products were ‘Spice Gold’, ‘Spice Silver’ and ‘Yucatan Fire’, but many other products have since appeared. The analytes detected, such as JWH‐018 and CP47,497 are experimental compounds, some of which were never designed for human use.Both ...
Simon, Hudson, John, Ramsey
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The Synthetic Cannabinoid Withdrawal Syndrome
Journal of Addiction Medicine, 2013Little is known about the effects of synthetic cannabinoids. There has been only one previous report of a withdrawal syndrome from synthetic cannabinoids. We report two cases of a withdrawal syndrome from prolonged habitual use of synthetic cannabinoids.Withdrawal from delta-9-THC has been described as a syndrome of anxiety, myalgias, chills, and ...
Nicholas, Nacca +5 more
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Metabolism of classical cannabinoids and the synthetic cannabinoid JWH‐018
Clinical Pharmacology & Therapeutics, 2015Although the putative pharmacological targets of synthetic cannabinoids (SCBs) abused in “K2” and “Spice” are similar to Δ9‐tetrahydrocannabinol (Δ9‐THC), it remains unclear why SCB toxicity is similar yet different from marijuana. There are obvious potency and efficacy differences, but also important metabolic differences that help explain the unique ...
M K, Su +3 more
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Plant, Synthetic, and Endogenous Cannabinoids in Medicine
Annual Review of Medicine, 2006Although used for more than 4000 years for recreational and medicinal purposes, Cannabis and its best-known pharmacologically active constituents, the cannabinoids, became a protagonist in medical research only recently. This revival of interest is explained by the finding in the 1990s of the mechanism of action of the main psychotropic cannabinoid ...
Di Marzo V, De Petrocellis L
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Eurasian Journal of Toxicology
Synthetic cannabinoids are defined as psychoactive substances that trigger the endocannabinoid system. They are largely used as narcotics, although some of their effects are used for therapeutic purposes. In the last decade, recreational use in Europe and the United States has increased more than other psychoactive substances.
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Synthetic cannabinoids are defined as psychoactive substances that trigger the endocannabinoid system. They are largely used as narcotics, although some of their effects are used for therapeutic purposes. In the last decade, recreational use in Europe and the United States has increased more than other psychoactive substances.
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Synthetic Cannabinoids as Drugs of Abuse
Current Drug Abuse Reviewse, 2012In the last decade a number of products have appeared in various countries that contain synthetic cannabinoids. This article reviews the history of the sale of these drugs, and the evidence that they contain synthetic cannabinoids. The biochemistry of the synthetic cannabinoids identified thus far is discussed, including a discussion of chemical ...
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