The clinical challenges of synthetic cathinones [PDF]
British Journal of Clinical Pharmacology, 2020 AimsWithin the new psychoactive substances (NPS) scenario, several hundred different molecules, mostly including synthetic cannabinoids and cathinones, have been identified so far. The aims of the paper were to: (i) identify the number of synthetic cathinones mentioned in a range of psychonaut, NPS‐related, online sources; and (ii) describe the ...
Fabrizio Schifano +2 more
exaly +7 more sources
Synthetic Cathinones and Neurotoxicity Risks: A Systematic Review [PDF]
International Journal of Molecular Sciences, 2023 According to the EU Early Warning System (EWS), synthetic cathinones (SCs) are the second largest new psychoactive substances (NPS) class, with 162 synthetic cathinones monitored by the EU EWS. They have a similar structure to cathinone, principally found in Catha Edulis; they have a phenethylamine related structure but also exhibit amphetamine-like ...
Alfredo Fabrizio Lo Faro +2 more
exaly +4 more sources
Synthetic cathinones related fatalities: an update [PDF]
European review for medical and pharmacological sciences, 2018 Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P. +5 more
core +4 more sources
A Quantitative LC–MS/MS Method for the Detection of 16 Synthetic Cathinones and 10 Metabolites and Its Application to Suspicious Clinical and Forensic Urine Samples [PDF]
Pharmaceuticals, 2022 Background: Synthetic cathinones currently represent one of the most predominant (sub)-classes of new psychoactive substance (NPS) in illicit drug markets.
Abdulaziz A. Aldubayyan +3 more
doaj +2 more sources
In Vitro Metabolic Study of Four Synthetic Cathinones: 4-MPD, 2-NMC, 4F-PHP and bk-EPDP [PDF]
Metabolites, 2022 The use of illicit drugs is exceedingly prevalent in society, and several of them can be illegally purchased from the internet. This occurrence is particularly augmented by the rapid emergence of novel psychoactive substances (NPS), which are sold and ...
Ivana Gavrilović +2 more
doaj +2 more sources
Clinical Pharmacology: Advances and Applications, 2013 Michael Capriola Thomasville Medical Center, Thomasville, NC, USA Abstract: The abuse of synthetic cathinones, widely known as bath salts, has been increasing since the mid-2000s.
Capriola M
doaj +5 more sources
Synthetic Cathinones Induce Developmental Arrest, Reduce Reproductive Capacity, and Shorten Lifespan in the C. elegans Model [PDF]
Journal of XenobioticsDrug abuse presents a significant global health challenge as the illicit drug market progresses from classic drugs to a growing prevalence of New Psychoactive Substances (NPS), particularly synthetic cathinones, which, although illegal, are often falsely
Cristina Mendes +5 more
doaj +2 more sources
Simultaneous Determination and Stability Analysis of Ten New Psychoactive Substances including Synthetic Cathinones, Phenethylamines, and Ketamine Substitutes in Urine Using Liquid Chromatography-Tandem Mass Spectrometry [PDF]
International Journal of Analytical Chemistry, 2023 Knowing the stability of drugs is important to ensure accurate and reliable results of drug concentrations. This study evaluated the stability of ten new psychoactive substances (NPSs) in urine and methanol/water at different storage temperatures ...
Feng-Shuo Yang +7 more
doaj +2 more sources
Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats [PDF]
Data in Brief, 2018 The synthetic cathinones methylone, butylone, and pentylone differ from each other through the one carbon lengthening of the α-alkyl chain: methylone (-CH3), butylone (-CH2CH3), and pentylone (-CH2CH2CH3) while 3,4-methylenedioxymethamphetamine (MDMA ...
Gregory G. Grecco +2 more
doaj +2 more sources
Toxicological Analysis of Intoxications with Synthetic Cathinones. [PDF]
J Anal Toxicol, 2022 Abstract Synthetic cathinones (SCs) are currently the second largest and the second most frequently seized group of new psychoactive substances. They are sold as replacements for controlled stimulants such as amphetamine, cocaine and 3,4-methylenedioxymethamphetamine.
Pieprzyca E, Skowronek R, Czekaj P.
europepmc +4 more sources