Results 11 to 20 of about 13,766,532 (237)
Size control and oscillations of active droplets in synthetic cells. [PDF]
Nat CommunOscillations in the formation and dissolution of molecular assemblies inside living cells are pivotal in orchestrating various cellular functions and processes. However, designing such rhythmic patterns in synthetic cells remains a challenge.
Sastre J +6 more
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Controlling Synthetic Cell-Cell Communication [PDF]
Frontiers in Molecular Biosciences, 2022 Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic cells,
Jefferson M. Smith +2 more
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Chemical Society Reviews, 2023 In this review, we summarize the strategies of inducing division in synthetic cells by using physical, chemical, and biological stimuli, and highlight the future challenges to the construction of autonomous synthetic cell division.
Mu-Yueh Chang +3 more
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Genetic encoding and expression of RNA origami cytoskeletons in synthetic cells. [PDF]
Nat NanotechnolThe central dogma at the core of molecular biology states that information flows from DNA to RNA and then to protein. Our research seeks to introduce a conceptually novel approach towards synthetic life by leveraging RNA origami, as an alternative to ...
Tran MP +6 more
europepmc +2 more sources
Coacervate Droplets for Synthetic Cells
Small Methods, 2023 AbstractThe design and construction of synthetic cells – human‐made microcompartments that mimic features of living cells – have experienced a real boom in the past decade. While many efforts have been geared toward assembling membrane‐bounded compartments, coacervate droplets produced by liquid–liquid phase separation have emerged as an alternative ...
Zi Lin +3 more
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A Role for Bottom-Up Synthetic Cells in the Internet of Bio-Nano Things? [PDF]
Molecules, 2023 The potential role of bottom-up Synthetic Cells (SCs) in the Internet of Bio-Nano Things (IoBNT) is discussed. In particular, this perspective paper focuses on the growing interest in networks of biological and/or artificial objects at the micro- and ...
Pasquale Stano +3 more
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Morphology remodelling and membrane channel formation in synthetic cells via reconfigurable DNA nanorafts. [PDF]
Nat MaterThe shape of biological matter is central to cell function at different length scales and determines how cellular components recognize, interact and respond to one another. However, their shapes are often transient and hard to reprogramme.
Fan S +6 more
europepmc +2 more sources
Light‐Based Juxtacrine Signaling Between Synthetic Cells [PDF]
Small ScienceCell signaling through direct physical cell–cell contacts plays vital roles in biology during development, angiogenesis, and immune response. Intercellular communication mechanisms between synthetic cells constructed from the bottom up are majorly ...
Hossein Moghimianavval +4 more
doaj +2 more sources
Light-controlled growth of DNA organelles in synthetic cells. [PDF]
Interface Focus, 2023 Living cells regulate many of their vital functions through dynamic, membraneless compartments that phase separate (condense) in response to different types of stimuli.
Agarwal S +3 more
europepmc +2 more sources
Light-Controlled Membrane Fusion in Synthetic Cells [PDF]
LifeLight-induced membrane fusion has become a pivotal technique for constructing and functionalizing synthetic cells by enabling precise control over membrane merging events.
Boying Xu, Adriano Caliari, Jian Xu
doaj +2 more sources