Results 21 to 30 of about 746,116 (250)
Journal of Biological Engineering, 2023 Background Efficient cell-free protein expression from linear DNA templates has remained a challenge primarily due to template degradation. In addition, the yields of transcription in cell-free systems lag behind transcriptional efficiency of live cells.
Christopher Deich +9 more
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Division in synthetic cells [PDF]
Emerging Topics in Life Sciences, 2019 Cell division is one of the most fundamental processes of life, and so far the only known way of how living systems can come into existence at all. Consequently, its reconstitution in any artificial cell system that will have to be built from the bottom-up is a notoriously complex but an important task.
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Synthetic multistability in mammalian cells [PDF]
Science, 2021 Abstract In multicellular organisms, gene regulatory circuits generate thousands of molecularly distinct, mitotically heritable states, through the property of multistability. Designing synthetic multistable circuits would provide insight into natural cell fate control circuit architectures and allow engineering of multicellular ...
Ronghui Zhu +3 more
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GeoV: An Open‐Source Software Package for Quantitative Image Analysis of 3D Vesicle Morphologies
Advanced Intelligent Systems, 2023 Bottom‐up synthetic biology has reconstituted processes like adhesion, cortex formation, or division of giant lipid vesicles (GUVs), which all rely on changes in the vesicle morphology.
Yannik Dreher +3 more
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STAR Protocols, 2023 Summary: Here, we present a protocol for controllable biomimetic mineralization at the nano-scale, simulating natural ion-enriched sedimentary mineralization. We describe steps for treatment of metal-organic frameworks with polyphenol-mediated stabilized
Xiaolong Zhan +8 more
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Regression plane concept for analysing continuous cellular processes with machine learning
Nature Communications, 2021 High-content screening prompted the development of software enabling discrete phenotypic analysis of single cells. Here, the authors show that supervised continuous machine learning can drive novel discoveries in diverse imaging experiments and present ...
Abel Szkalisity +16 more
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Rethinking governance of synthetic cells
Frontiers in Bioengineering and BiotechnologySynthetic cells represent a class of engineered biological systems that span a continuum from non-replicating biochemical assemblies to genome-containing entities, exposing limitations in conventional approaches to biotechnology governance. These systems
David R. Gillum +3 more
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Synthetic biology of minimal living cells: primitive cell models and semi-synthetic cells [PDF]
Systems and Synthetic Biology, 2010 This article summarizes a contribution presented at the ESF 2009 Synthetic Biology focused on the concept of the minimal requirement for life and on the issue of constructive (synthetic) approaches in biological research. The attempts to define minimal life within the framework of autopoietic theory are firstly described, and a short report on the ...
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Molecular Communication Approaches for Wetware Artificial Life: A Workshop Report
ProceedingsOn 25 July 2023, a workshop entitled “Molecular Communication Approaches for Wetware Artificial Life” took place as a satellite event at the international conference ALIFE 2023 (The 2023 Conference on Artificial Life).
Pasquale Stano +7 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
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