Results 11 to 20 of about 746,116 (250)
Reprogramming cells with synthetic proteins
Asian Journal of Andrology, 2015 Conversion of one cell type into another cell type by forcibly expressing specific cocktails of transcription factors (TFs) has demonstrated that cell fates are not fixed and that cellular differentiation can be a two-way street with many intersections ...
Xiaoxiao Yang, Vikas Malik, Ralf Jauch
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Synthetic Biology: A Bridge between Artificial and Natural Cells
Life, 2014 Artificial cells are simple cell-like entities that possess certain properties of natural cells. In general, artificial cells are constructed using three parts: (1) biological membranes that serve as protective barriers, while allowing communication ...
Yunfeng Ding, Fan Wu, Cheemeng Tan
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Chemical Society Reviews, 2023 In this review, we summarize the strategies of inducing division in synthetic cells by using physical, chemical, and biological stimuli, and highlight the future challenges to the construction of autonomous synthetic cell division.
Mu-Yueh Chang +3 more
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Morphogenesis in Synthetic Chemical Cells [PDF]
The Journal of Physical Chemistry Letters, 2022 We present an efficient model for describing morphogenesis and the emergence of spatiotemporal structures in synthetic chemical cells. This work is motivated by an experimental setup used for testing Turing's theory of morphogenesis. The model developed is based on the general theory of chemically active droplets, which combines the classical theory of
Leonardo Silva-Dias +1 more
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Frontiers in Communications and Networks, 2021 In this Perspective article we intend to focus on the opportunity of modelling Shannon information and/or “semantic” information in the field originated by the convergence of bottom-up synthetic biology (in particular, the construction of “synthetic ...
Maurizio Magarini, Pasquale Stano
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A Role for Bottom-Up Synthetic Cells in the Internet of Bio-Nano Things?
Molecules, 2023 The potential role of bottom-up Synthetic Cells (SCs) in the Internet of Bio-Nano Things (IoBNT) is discussed. In particular, this perspective paper focuses on the growing interest in networks of biological and/or artificial objects at the micro- and ...
Pasquale Stano +3 more
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Synthetic Genomics From a Yeast Perspective
Frontiers in Bioengineering and Biotechnology, 2022 Synthetic Genomics focuses on the construction of rationally designed chromosomes and genomes and offers novel approaches to study biology and to construct synthetic cell factories.
Charlotte C. Koster +5 more
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Towards a synthetic cell cycle [PDF]
Nature Communications, 2021 AbstractRecent developments in synthetic biology may bring the bottom-up generation of a synthetic cell within reach. A key feature of a living synthetic cell is a functional cell cycle, in which DNA replication and segregation as well as cell growth and division are well integrated. Here, we describe different approaches to recreate these processes in
Lorenzo Olivi +8 more
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Gene-Expressing Liposomes as Synthetic Cells for Molecular Communication Studies
Frontiers in Bioengineering and Biotechnology, 2019 The bottom-up branch of synthetic biology includes—among others—innovative studies that combine cell-free protein synthesis with liposome technology to generate cell-like systems of minimal complexity, often referred to as synthetic cells.
Giordano Rampioni +3 more
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Synthetic Cell as a Platform for Understanding Membrane-Membrane Interactions
Membranes, 2021 In the pursuit of understanding life, model membranes made of phospholipids were envisaged decades ago as a platform for the bottom-up study of biological processes.
Bineet Sharma +3 more
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