Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
The effect of dietary calcium and other nutritionally relevant divalent cations on fatty acid-soap formation : a dissertation presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Nutritional Sciences at Massey University, Manawatū, New Zealand [PDF]
A growing amount of scientific evidence appears to support a relationship between dietary calcium (Ca) and body weight where increased dietary Ca intake leads to weight reduction and the faecal excretion of several fatty acids.
Stroebinger, Natascha
core
Laser‐Induced Graphene from Waste Almond Shells
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
How Close Are We to the Production of Milk in Alternative Systems? The Fat Perspective
The growing demand for sustainable food systems has led to significant advancements in developing alternatives to animal-derived products. Dairy products are an important dietary source of proteins and fats; however, their production raises environmental
Roni Tadmor-Levi, Nurit Argov-Argaman
doaj +1 more source
Triacylglycerol synthesis in rat adipose tissue : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
Adipose tissue consists of two types of cell; the adipocyte and the non-adipocyte {Rodbell, 1964). The adipocyte is unique amongst mammalian cell types in that one class of component {TG) comprises up to 80% of its weight.
Wilson, Russell Douglas
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Unleashing the Power of Machine Learning in Nanomedicine Formulation Development
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore +7 more
wiley +1 more source
EPR Studies on the Properties of Model Photoreceptor Membranes Made of Natural and Synthetic Lipids. [PDF]
Duda M +4 more
europepmc +1 more source
The biosynthesis of galactolipids in red clover (Trifolium pratense) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry [PDF]
Galactolipids occur in all cells capable of the photosynthetic evolution of oxygen. The main galactolipids are monogalactosyl diglyceride (MGDG), digalactosyldiglyceride (DGDG) and sulfolipid (SL), MGDG being the most abundant.
Bycroft, Wesley
core
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava +7 more
wiley +1 more source

