Results 121 to 130 of about 136,463 (299)

Control of Supramolecular Phenomena via Molecular Motors [PDF]

open access: yes, 2010
My research concentrated on the amplification of chirality. This means that a chiral molecule (which has a mirror image) influences several surrounding non chiral molecules in such a way as to generate chirality on a larger scale.
Jongejan, Mahthild Gwendolyn Maria,   +1 more
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Vibrational Spectroscopy of Self-Forming Synthetic PEGylated Lipids and Nanovesicles

open access: yes, 2018
Vibrational spectroscopy has been used to elucidate the structure and conformation of lipids and nanovesicles. In this study, three different vibrational spectroscopic techniques, namely near-infrared (NIR), Fourier transform infrared (FTIR) and Raman ...
Bista, Rajan K.
core  

Taste reception in a synthetic lipid membrane.

open access: yesmembrane, 1987
The effect of taste stimulants on a DOPH (dioleyl phosphate) Millipore membrane was investigated as a model system of taste reception. Quinine, HCl, NaCl and sucrose were chosen as bitter, sour, salty and sweet substances, respectively. From the measurements of membrane potential and membrane resistance, it is conceivable that quinine, HCl and NaCl ...
Satoru Iiyama   +2 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Effect of lipids on biomass development in anaerobic fixed-bed reactors treating a synthetic dairy waste [PDF]

open access: yes, 1997
The aim of this work was to follow the evolution in quantity and quality of the biomass developed during the operation of two anaerobic fixed bed reactors treating a synthetic dairy waste with different lipid contents.
Pereira, R. M. Álvares   +3 more
core  

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin   +14 more
wiley   +1 more source

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