Results 101 to 110 of about 136,463 (299)
Safety and biodistribution of sulfated archaeal glycolipid archaeosomes as vaccine adjuvants
Human Vaccines & Immunotherapeutics, 2018 Archaeosomes are liposomes comprised of ether lipids derived from various archaea. Unlike conventional ester-linked liposomes, archaeosomes exhibit high pH and thermal stability. As adjuvants, archaeosomes can induce robust, long-lasting humoral and cell-
Bassel Akache +6 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2023 Triacylglycerol estolides (TG-EST) are biologically active lipids extensively studied for their anti-inflammatory and anti-diabetic properties. In this work, eight standards of TG-EST were synthesized and systematically investigated by nanoelectrospray ...
Aleš Machara +14 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Bioactive compounds in plants: a new food perspective
, 2018 Antioxidants refer to a group of compounds that are able to delay or inhibit the oxidation of lipids or other biomolecules, and thus prevent or repair the damage of body cells caused by oxygen (Shahidi and Naczk, 2004; Tachakittirungrod et al., 2007 ...
Ricci Antonella +3 more
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Chemical synthesis of ω- hydroxyderivatives of plant fatty acid substrates.
Тонкие химические технологии, 2006 A common synthetic procedure for the synthesis of (9Z,12Z)-18-hydroxy-9,12- octadecadienoic acid (18-HODE) and (9Z,12Z,15Z)-18-hydroxy-9,12,15- octadecatrienoic acid (18-HOTrE) – analogues of substrates of plant lipids oxygenation was developed.
N. V. Groza +3 more
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Lxr-driven enterocyte lipid droplet formation delays transport of ingested lipids[S]
Journal of Lipid Research, 2014 Liver X receptors (Lxrs) are master regulators of cholesterol catabolism, driving the elimination of cholesterol from the periphery to the lumen of the intestine.
Lourdes Cruz-Garcia, Amnon Schlegel
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FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Synthesis of diglycerides containing polyunsaturated fatty acids
Тонкие химические технологии, 2012 Synthetic approaches to obtain diglycerides containing polyunsaturated fatty acids at C(2 ) position of glycerol were developed. These compounds can be used to generate antitumor lipids and enzymatically triggered liposomes .
M. S. Tsapleva +2 more
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