Results 241 to 250 of about 136,463 (299)

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Tools For Building Artificial Biological Nanostructures. [PDF]

ACS Nano
Bradford TS, Hutchings S, Liston JD, Pakosz-Stepien Z, Sanderson A, Shaukat A, Bentham A, Lin TY, Stepien P, Heddle JG.   +9 more
europepmc   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Cell-Derived Nanocarriers for Monocyte-Mediated Therapeutic Delivery: Concept and Challenges. [PDF]

Yonsei Med J
Yu SE, Kim J, Sung HJ.
europepmc   +1 more source

Electrical Stimulation Directs Formation of Perfused Vasculature in Engineered Tissues

Advanced Science, EarlyView.
Electrical stimulation (ESTIM) enhances vasculature formation in engineered human tissues. In 3D endothelial‐fibroblast constructs, conditioning with ESTIM promotes the formation of dense and highly branched networks that rapidly anastomose with mouse vasculature when implanted in vivo. Vessels formed under ESTIM are importantly functionally perfusable.
Katarzyna A. Grzelak, Ashley D. Westerfield, Vardhman Kumar, Kasturi Chakraborty, Navaneeth Krishna Rajeeva Pandian, Christopher S. Chen, Sangeeta N. Bhatia   +6 more
wiley   +1 more source

Meta-Learning as a Promising Strategy for Lipid Nanoparticle Optimization and Ionizable Lipid Discovery. [PDF]

Nano Lett
Sieber-Schäfer F, Hagedorn L, Reger L, Möbius K, Winkeljann B, Merkel OM.   +5 more
europepmc   +1 more source

RNA-Loaded Nanoparticles for Targeted Lung Delivery. [PDF]

Biomedicines
Siringan MJ, Chen X, Huo J.
europepmc   +1 more source

POx-Lipids as an Alternative to PEG-Lipids? Multimethod Assessment of Chemistry and Structure. [PDF]

Anal Chem
Tsarenko E, Anufriev I, Holick CT, Klein T, Schubert S, Fritz N, Hoeppener S, Schubert US, Nischang I.   +8 more
europepmc   +1 more source

Effects of Sample Deposition Medium and Drying on Spectroscopic Quantification of Lipid Biomarkers in Respiratory Distress Syndrome. [PDF]

Biosensors (Basel)
Luo ZH, Ahmed W, Postle AD, Dushianthan A, Grocott MPW, Senthil Murugan G.   +5 more
europepmc   +1 more source