Results 131 to 140 of about 20,853,741 (308)

Supporting policy analysis in the Dutch rail sector using System Dynamics

open access: yes, 2013
With a sizeable expected growth of demand for rail transport in the Netherlands in the coming decades, and limited resources for expansion of the rail network, intensified utilization of the infrastructure is to be expected.
Mannaerts, A. (author)   +7 more
core   +1 more source

On the design of hybrid simulation models, focussing on the agent-based system dynamics combination [PDF]

open access: yes, 2014
©Cranfield University, 2014There is a growing body of literature reporting the application of hybrid simulations to inform decision making. However, guidance for the design of such models, where the output depends upon more than one modelling paradigm ...
Swinerd, Chris
core   +1 more source

Methods for Project Tracking in Creative Environment

open access: yesActa Informatica Pragensia, 2017
The objective of this paper is to design new alternative methods for project tracking in creative industry environment. One of the research method is system dynamics modelling.
Eva Šviráková
doaj   +1 more source

System dynamics modelling of health workforce planning to address future challenges of Thailand's Universal Health Coverage. [PDF]

open access: yesHum Resour Health, 2021
Leerapan B   +8 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Scarcity of Minerals and Metals: A Generic Exploratory System Dynamics Model

open access: yes, 2010
Possible short, medium and/or long term scarcity of minerals/metals may actually pose a threat to modern societies. Its potentially disruptive societal consequences qualify this issue for exploration from a world/regional security point of view.
Pruyt, E. (author), Pruyt, E.
core   +1 more source

Correction to: System dynamics modelling of health workforce planning to address future challenges of Thailand's Universal Health Coverage. [PDF]

open access: yesHum Resour Health, 2021
Leerapan B   +8 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Resilient by design: a modelling approach to support scenario and policy analysis in the Olifants River Basin, South Africa

open access: yes, 2016
In this paper, we report on a concerted modelling effort in the South African water resources sector in which system dynamics provides the paradigmatic framing for both a stakeholder engagement process and for developing an underpinning, integrative ...
Pollard, S (author)   +7 more
core  

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