Results 161 to 170 of about 136,148 (315)
Using group model building to support strategic sustainable development
, 2020 This paper discusses how group model building can be used to support strategic sustainable development. Four cases in which causal loop diagrams and, or, system dynamics have been used are described. In addition, some recent and adjacent research studies
Ny, Henrik +2 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Correction to: Using system dynamics modelling to estimate the costs of relaxing health system constraints: a case study of tuberculosis prevention and control interventions in South Africa. [PDF]
Health Policy Plan, 2023 europepmc +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Accurate macroscale modelling of spatial dynamics in multiple dimensions
, 2012 Developments in dynamical systems theory provides new support for the macroscale modelling of pdes and other microscale systems such as Lattice Boltzmann, Monte Carlo or Molecular Dynamics simulators.
Bunder, J. E. +2 more
core
Purpose Cost escalation has been identified as one of the most significant challenges and recurring issues in the delivery of social and economic infrastructure in the Nigerian public sector.
Ahmed, Sa’id Namadi +4 more
core +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
This paper presents a new approach for the modelling of a screw shaft including the axial and torsional dynamics in the same model. The model includes the distributed parameter dynamics of the ball screw system and the effect of mass distribution.
Pislaru, Crinela +2 more
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System dynamics modelling of urbanization under energy constraints in China. [PDF]
Sci Rep, 2020 Gu C +6 more
europepmc +1 more source