System dynamics modelling - Open Access .click

Results 171 to 180 of about 20,853,741 (308)

Food packaging: identifying the socio-economic drivers and reduction opportunities through system dynamics modelling. [PDF]

Global Health
Chakori S, Aziz AA, Richards R.
europepmc +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source

Determinants, Pathways, and Outcomes of Health Literacy in India: A System Dynamics Modelling Study. [PDF]

Cureus
B A, Hassan F, Jaison A.
europepmc +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero +1 more
wiley +1 more source

Using Difference Equation to Model Discrete-time Behavior in System Dynamics Modeling

, 2014
In system dynamics modeling, differential equations have been used as the basic mathematical operator. Using difference equation to build system dynamics models instead of differential equation, can be insightful for studying small organizations or ...
Ghorbani, A. +5 more
core +1 more source

System dynamics modelling methods for public health policy evaluation: a systematic literature review focussing on mental health and substance use disorders. [PDF]

BMC Public Health
Valkenburg HJ +5 more
europepmc +1 more source

Performance of geotextile-based slow sand filter media in removing total coli for drinking water treatment using system dynamics modelling. [PDF]

Heliyon, 2020
Fitriani N +8 more
europepmc +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park +3 more
wiley +1 more source

Revealed: The Underlying Flow, Masked by Predictive Risk Tools but Uncovered by Dynamic Simulation used in Joint Commissioning

International Journal of Integrated Care, 2015
Douglas McKelvie, Steve Arnold, Terry Dafter +2 more
doaj +3 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source

system dynamics
systems thinking
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civil engineering general
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computer science - machine learning