Results 121 to 130 of about 56,728,962 (299)

Developing and validating PubMed infant hedges for PubMed and Ovid MEDLINE: a Medical Library Association pediatrics librarians caucus initiative

open access: yesJournal of the Medical Library Association
Background: To support evidence synthesis and clinical searching, a team of librarians developed and validated infant age (birth to 23 months) search hedges for PubMed (National Library of Medicine) and Medline (OVID).
Lynn Kysh   +5 more
doaj   +1 more source

Systematic reviews and cancer research: a suggested stepwise approach

open access: yesBMC Cancer, 2018
Systematic reviews, with or without meta-analysis, play an important role today in synthesizing cancer research and are frequently used to guide decision-making.
George A. Kelley, Kristi S. Kelley
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Systematic reviews, ‘systematic reviews’ and more: When variation leads to confusion

open access: yes, 2018
Original research is important for informing health care and policy but a critical synthesis of the literature is important1 and should incorporate a full and impartial review “to remove a great deal of rubbish”.2 The early 1990s saw the introduction of ...
Marshall, Andrea P
core   +1 more source

A descriptive analysis of child-relevant systematic reviews in the Cochrane Database of Systematic Reviews [PDF]

open access: yes, 2013
Background: Systematic reviews (SRs) are considered an important tool for decision-making. There has been no recent comprehensive identification or description of child-relevant SRs. A description of existing child-relevant SRs would help to identify the
Moher, David   +7 more
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

The searchbuildR shiny app: A new implementation of the objective approach for search strategy development in systematic reviews

open access: yesCochrane Evidence Synthesis and Methods
Introduction One of the main tasks in information retrieval is the development of Boolean search strategies for systematic searches in bibliographic databases. This includes the identification of free‐text terms and controlled vocabulary.
Claudia Kapp   +5 more
doaj   +1 more source

Traditional Chinese Medicine for childhood obesity: an umbrella review of systematic reviews and meta-analyses

open access: yesFrontiers in Medicine
BackgroundChildhood obesity is a major global public health concern associated with adverse cardiometabolic outcomes and long-term health risks. While conventional treatments such as diet, exercise, and behavioral therapy remain the cornerstone of ...
Yuanyuan He   +6 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Music Therapy for Managing Dental Anxiety in Children: A Systematic Review and Meta-Analysis of Clinical Evidence

open access: yesChildren
Background: Dental anxiety is a common challenge in paediatric dentistry, often leading to avoidance of treatment and compromised oral health. Non-pharmacological interventions such as music therapy have gained increasing attention as safe and cost ...
Laura Marqués-Martínez   +5 more
doaj   +1 more source

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