Results 131 to 140 of about 56,728,962 (299)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Systematic Reviews Informing Occupational Therapy

, 2013
OBJECTIVE. We sought to identify and describe the number, topic, and publishing trends of systematic reviews relevant to occupational therapy indexed in the OTseeker ...
Tooth, Leigh, Hoffmann, Tammy, McCluskey, Annie, Coghlan, Nicole, Bennett, Sally, Hoffmann, Tammy; id_orcid   +5 more
core   +1 more source

Dietary fiber consumption and outcomes of different cancers: an umbrella review

Food & Nutrition Research
Background: The relationship between dietary fiber intake and cancer outcomes, including incidence, recurrence, and mortality, is crucial for understanding cancer prevention strategies.
Xingyu He, Jiayi Hou, Lei Liu, Xin Chen, Lijie Zhang, Caojia Pang, Yu Tong, Hongling Li, Feng Chen, Rong Peng, Zheng Shi   +10 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The new rehabilitation definition for research purposes could improve rehabilitation description in Cochrane Systematic Reviews

Cochrane Evidence Synthesis and Methods
Introduction In 2022, Cochrane Rehabilitation developed a new definition of rehabilitation for research purposes with 80 global stakeholders, aiming to support and improve the production and reporting of primary and evidence‐synthesis rehabilitation ...
Irene Battel, Chiara Arienti, William Levack, Carlotte Kiekens, Stefano Negrini   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Knowledge and Attitudes of Dental Professionals and Students on MIH: A Scoping Review

Acta Stomatologica Croatica
Objective: This scoping review aimed to map the knowledge, perceptions, and attitudes of dental professionals and students regarding MIH. Materials and Methods: A systematic search was conducted in the electronic databases MEDLINE/PubMed, Scopus, Web of ...
Juan Sebastian Lara, Manuel Restrepo, Jose Luis Ureña-Cirett, Janina Rodrigues, Nathalia Araujo Bim, Bruna Bergamo Campoi, Esperanza Ángeles Martínez-Mier, Tamara Kerber Tedesco   +7 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Wastewater-Based Epidemiology for Infectious Disease Surveillance: A Systematic Review and Meta-Analysis Focused on SARS-Cov-2, with Narrative Synthesis for Other Pathogens [PDF]

Journal of Environmental Health and Sustainable Development
Introduction: Wastewater-based epidemiology (WBE) has emerged as a valuable approach for environmental management and public health surveillance. By detecting viral RNA and biomarkers in wastewater, WBE provides community-level early warning signals that
Soleiman Forouzandeh, Amin Salehi-Abargouei, Ali Asghar Ebrahimi   +2 more
doaj