Results 61 to 70 of about 815,105 (301)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Conclusions in systematic reviews of mammography for breast cancer screening and associations with review design and author characteristics

Systematic Reviews, 2017
Background Debates about the benefits and harms of mammography continue despite the accumulation of evidence. We sought to quantify the disagreement across systematic reviews of mammography and determine whether author or design characteristics were ...
Smriti Raichand, Adam G. Dunn, Mei-Sing Ong, Florence T. Bourgeois, Enrico Coiera, Kenneth D. Mandl   +5 more
doaj   +1 more source

Analgesic medicines for adults with low back pain: protocol for a systematic review and network meta-analysis

Systematic Reviews, 2020
Background There is limited evidence for the comparative effectiveness of analgesic medicines for adults with low back pain. This systematic review and network meta-analysis aims to determine the analgesic effect, safety, acceptability, effect on ...
Michael A. Wewege, Matthew K. Bagg, Matthew D. Jones, James H. McAuley, The ANiMALIA investigators   +4 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Effects of zinc supplementation on sleep quality in humans: A systematic review of randomized controlled trials

Health Science Reports
Background and Aims Alternative therapies, such as zinc supplementation, have been explored as potential interventions for sleep disorders. However, the efficacy of zinc supplementation in improving sleep quality remains uncertain. This systematic review
Mostafa Shahraki Jazinaki, Alireza Gheflati, Mohammad Reza Shadmand Foumani Moghadam, Saeid Hadi, Maryam Razavidarmian, Masoud Yaghob Nezhad, Hale Akhtari, Mona Nematizadeh, Mohammad Safarian   +8 more
doaj   +1 more source

Quality of systematic reviews on the treatment of vesiculobullous skin diseases. A meta-epidemiological study [PDF]

Anais Brasileiros de Dermatologia
Background Systematic reviews of Randomized Controlled Trials (RCTs) are considered high-level evidence to support a decision on therapeutic interventions, and their methodological quality is essential to provide reliable and applicable results ...
Kamilla Mayr Martins Sá, Juliana Cavaleiro Rodrigues, Lígia Borges da Silva, Giovanna Marcılio Santos, Mileny Esbravatti Stephano Colovati, Ana Luiza Cabrera Martimbianco   +5 more
doaj   +1 more source

Study-based registers of randomized controlled trials: Starting a systematic review with data extraction or meta-analysis [PDF]

BioImpacts, 2017
Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented.
Farhad Shokraneh, Clive Elliott Adams
doaj   +1 more source

Staying at the front line of literature: How can topic modelling help researchers follow recent studies?

Frontline Learning Research, 2021
Staying at the front line in learning research is challenging because many fields are rapidly developing. One such field is research on the temporal aspects of computer-supported collaborative learning (CSCL).
Joni Lämsä, Catalina Espinoza, Ari Tuhkala, Raija Hämäläinen   +3 more
doaj   +1 more source

Job satisfaction in hotel employess: a systematic review of the literature [PDF]

, 2016
Hotel employees' job satisfaction is very important to their performance. In a systematic review of the previous literature on hotel employees, it was found that the most studied variable was job satisfaction; there were no other systematic reviews on ...
Borralha, Sérgio, Jesus, Saúl, Pinto, Patrícia, Viseu, J.   +3 more
core  

Optimizing the real-world impact of rehabilitation reviews: increasing the relevance and usability of systematic reviews in rehabilitation [PDF]

, 2019
BACKGROUND: Despite a growing portfolio of rehabilitation reviews, uptake of review findings into practice remains slow, with review findings perceived to be lacking in relevance and usability for stakeholders.
Bright, Felicity A, Kayes, Nicola M, Kersten, Paula, Martin, Rachelle A, Pollock, Alex   +4 more
core   +2 more sources