Results 71 to 80 of about 53,975,838 (284)

Scientific hypotheses can be tested by comparing the effects of one treatment over many diseases in a systematic review [PDF]

, 2014
Objectives: To describe the use of systematic reviews or overviews (systematic reviews of systematic reviews) to synthesize quantitative evidence of intervention effects across multiple indications (multiple-indication reviews) and to highlight issues ...
Lilford, Richard, Chen, Yen-fu; id_orcid, Hemming, Karla, Hemming, K, Chilton, Peter J., Altman, DG, Hemming, Karla; id_orcid, Altman, Douglas G., Gupta, Keshav K., Gupta, KK, Chen, Yen-Fu, Chilton, PJ, Lilford, RJ, Chen, Y-F.‏‎, Chen, YF, Lilford, Richard J.   +15 more
core   +1 more source

Quality of systematic reviews on the treatment of vesiculobullous skin diseases. A meta-epidemiological study [PDF]

Anais Brasileiros de Dermatologia
Background Systematic reviews of Randomized Controlled Trials (RCTs) are considered high-level evidence to support a decision on therapeutic interventions, and their methodological quality is essential to provide reliable and applicable results ...
Kamilla Mayr Martins Sá, Juliana Cavaleiro Rodrigues, Lígia Borges da Silva, Giovanna Marcılio Santos, Mileny Esbravatti Stephano Colovati, Ana Luiza Cabrera Martimbianco   +5 more
doaj   +1 more source

Analgesic medicines for adults with low back pain: protocol for a systematic review and network meta-analysis

Systematic Reviews, 2020
Background There is limited evidence for the comparative effectiveness of analgesic medicines for adults with low back pain. This systematic review and network meta-analysis aims to determine the analgesic effect, safety, acceptability, effect on ...
Michael A. Wewege, Matthew K. Bagg, Matthew D. Jones, James H. McAuley, The ANiMALIA investigators   +4 more
doaj   +1 more source

Study-based registers of randomized controlled trials: Starting a systematic review with data extraction or meta-analysis [PDF]

BioImpacts, 2017
Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented.
Farhad Shokraneh, Clive Elliott Adams
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Topical statins in the treatment of porokeratosis: a systematic review

Clinical and Experimental Dermatology
Abstract Porokeratosis is a chronic disorder of keratinization associated with significant morbidity and no spontaneous resolution. Currently, there are no therapies approved by the US Food and Drug Administration (FDA). However, the off-label use of topical statins – targeting the mevalonate pathway – has shown promise as a novel ...
Jeff, Martini, Maria Gnarra, Buethe, Lihi, Atzmony   +2 more
openaire   +2 more sources

Topical haemostatic agents for skin wounds: a systematic review [PDF]

BMC Surgery, 2011
Abstract Background Various agents and techniques have been introduced to limit intra-operative blood loss from skin lesions. No uniformity regarding the type of haemostasis exists and this is generally based on the surgeon's preference.
Groenewold, M.D., Gribnau, A.J., Ubbink, D.T.   +2 more
openaire   +5 more sources

Assessing quality in systematic reviews of the effectiveness of health promotion: areas of consensus and dissension

, 2009
Systematic reviews have played an increasingly important role in health promotion in recentyears. Yet there are debates about how they should be conducted, particularly about how thequality of evidence should be assessed.
Shepherd, Jonathan Paul
core   +1 more source