Results 81 to 90 of about 56,728,962 (299)

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling   +2 more
wiley   +1 more source

Systematic reviews: what do they involve?

open access: yes, 1997
Systematic reviews are a source of evidence to guide practice and identify the need for future research. This article gives an outline of the methods involved in conducting systematic reviews, including the identification of a review topic, searching ...
Bannigan, K, Entwistle, V, Droogan, J
core   +3 more sources

Development and validation of high-sensitivity and high-specificity pubmed search filters for systematic and non-systematic reviews

open access: yesBMC Medical Research Methodology
Objective To develop and compare the accuracy of different PubMed search strategies (filters) for systematic and non-systematic reviews in dental journals. Methods This validation study included articles published in 2019 in 15 dental journals.
Victor Nascimento Fontanive   +4 more
doaj   +1 more source

Efficacy and safety of systemic morphine for persistent breathlessness in adults with advanced nonmalignant disease: a systematic review and meta-analysis of randomized trials

open access: yesPalliative Medicine in Practice
BACKGROUND: Morphine is used for persistent breathlessness despite uncertainty about its efficacy and safety in advanced nonmalignant diseases. We evaluated its symptomatic, functional, physiologic, and adverse effects. METHODS: We conducted a systematic
Roxana Valentina Barrezueta Román   +2 more
doaj   +1 more source

Structured approach with primary and secondary survey for major trauma care: an overview of reviews

open access: yesWorld Journal of Emergency Surgery, 2023
Background A structured approach involves systematic management of trauma patients. We aim to conduct an overview of reviews about the clinical efficacy and safety of structured approach (i.e., primary and secondary survey) by guideline checklist ...
Silvia Gianola   +17 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Topical statins in the treatment of porokeratosis: a systematic review

open access: yesClinical and Experimental Dermatology
Abstract Porokeratosis is a chronic disorder of keratinization associated with significant morbidity and no spontaneous resolution. Currently, there are no therapies approved by the US Food and Drug Administration (FDA). However, the off-label use of topical statins – targeting the mevalonate pathway – has shown promise as a novel ...
Jeff, Martini   +2 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Systematic Reviews

open access: yes, 2015
Systematic reviews are a type of literature review in which authors systematically search for, critically appraise, and synthesize evidence from several studies on the same topic (Grant & Booth, 2009).
Milner, Kerry A.
core   +1 more source

The effectiveness of interventions to change six health behaviours: a review of reviews [PDF]

open access: yes, 2010
Background Several World Health Organisation reports over recent years have highlighted the high incidence of chronic diseases such as diabetes, coronary heart disease and cancer.
Harris Fiona M   +17 more
core   +2 more sources

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