Results 91 to 100 of about 2,603,757 (311)

Profiling the Resident and Infiltrating Monocyte/Macrophages during Rejection following Kidney Transplantation

Journal of Immunology Research, 2020
Immune tolerance research is essential for kidney transplantation. Other than antibody and T cell-mediated immune rejection, macrophage-mediated innate immunity plays an important role in the onset phase of transplantation rejection.
Jie Wang, Peiling Luo, Jingjie Zhao, Junhua Tan, Feifan Huang, Ruiying Ma, Peng Huang, Meiying Huang, Yuming Huang, Qiuju Wei, Liuzhi Wei, Zechen Wang, Lingzhang Meng   +12 more
doaj   +1 more source

The relationship between the insulin-like growth factor-1 axis, weight loss, an inflammation-based score and survival in patients with inoperable non-small cell lung cancer [PDF]

, 2010
<b>Background & aims:</b> The involvement of a systemic inflammatory response, as evidenced by the Glasgow Prognostic Score (GPS), is associated with weight loss and poor outcome in patients with non-small cell lung cancer.
Meek, C.L., Wallace, A.M., McMillan, D.C., Forrest, L.M.   +3 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2

Frontiers in Immunology, 2018
Bullous pemphigoid (BP), the most frequent autoimmune bullous disorder, is a paradigmatic autoantibody-mediated disease associated with autoantibodies against BP180 (type XVII collagen, Col17).
Christian M. Karsten, Tina Beckmann, Maike M. Holtsche, Jenny Tillmann, Sabrina Tofern, Franziska S. Schulze, Eva Nina Heppe, Ralf J. Ludwig, Detlef Zillikens, Inke R. König, Jörg Köhl, Jörg Köhl, Enno Schmidt, Enno Schmidt   +13 more
doaj   +1 more source

Sarcopenia correlates with systemic inflammation in COPD

, 2017
Min Kwang Byun,1 Eun Na Cho,1 Joon Chang,2 Chul Min Ahn,1 Hyung Jung Kim1 1Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, 2Division of Pulmonology, Department of Internal Medicine, Severance Hospital, Yonsei ...
Ahn CM, Byun MK, Kim HJ, Chang J, Cho EN
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Systemic Immune-Inflammation and Systemic Inflammation Response Indices are Predictive Markers of Mortality in Inpatients Internal Medicine Services

International Journal of General Medicine, 2023
Betül Çavuşoğlu Türker,1 Süleyman Ahbab,1 Fatih Türker,1 Emre Hoca,1 Ece Çiftçi Öztürk,1 Atay Can Kula,2 Hüseyin Öztürk,3 Ayşe Öznur Urvasızoğlu,1 Merve Bulut,4 Özge Yasun,5 Hayriye Esra Ataoğlu1 1Department of ...
Çavuşoğlu Türker B, Ahbab S, Türker F, Hoca E, Çiftçi Öztürk E, Kula AC, Öztürk H, Urvasızoğlu AÖ, Bulut M, Yasun Ö, Ataoğlu HE   +10 more
doaj  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Complement tumor-crosstalk: the role of C5a receptors in urothelial carcinomas

Frontiers in Immunology
Urothelial carcinoma, the second most common urological malignancy, can arise in both the lower and upper urinary tract, with approximately 90–95% arising in the bladder, while urothelial carcinomas of the upper urinary tract account for only 5–10 ...
Lea Sophie Lütje, Caroline Gruner, Christian Marcel Karsten, Axel Stuart Merseburger, Marie Christine Roesch   +4 more
doaj   +1 more source