Results 11 to 20 of about 2,603,757 (311)

C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection

open access: yesFrontiers in Immunology, 2020
Toxoplasma gondii (T. gondii) is a parasite infecting animals and humans. In intermediate hosts, such as humans or rodents, rapidly replicating tachyzoites drive vigorous innate and adaptive immune responses resulting in bradyzoites that survive within ...
Daria Briukhovetska   +8 more
doaj   +1 more source

IL-10 revisited in systemic lupus erythematosus

open access: yesFrontiers in Immunology, 2022
IL-10 is a cytokine with pleiotropic functions, particularly known for its suppressive effects on various immune cells. Consequently, it can limit the pathogenesis of inflammatory diseases, such as multiple sclerosis (MS), inflammatory bowel disease ...
Swayanka Biswas   +2 more
doaj   +1 more source

The new face of HFpEF: systemic inflammation [PDF]

open access: yes, 2023
Systemic inflammation is proposed as background of development and progres of heart failure, especially in heart failure with preserved ejection fraction (HFpEF).
Lelonek, Małgorzata; Department of Noninvasive Cardiology, Medical University of Lodz, Łódź, Poland
core   +1 more source

High-Fat Diet : Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse [PDF]

open access: yes, 2010
Background: Obesity induced by high fat (HF) diet is associated with inflammation which contributes to development of insulin resistance. Most prior studies have focused on adipose tissue as the source of obesity-associated inflammation.
Ding, Shengli   +7 more
core   +6 more sources

Alterations of the Gut Microbiome in Chinese Zhuang Ethnic Patients with Sepsis

open access: yesMediators of Inflammation, 2022
Objectives. Sepsis is characterized as a dysregulated host immune response to infection and has been known to be closely associated with the gut microbiome.
Jieyang Yu   +8 more
doaj   +1 more source

The Melanocortin System in Control of Inflammation [PDF]

open access: yesThe Scientific World JOURNAL, 2010
Melanocortin peptides, the collective term for α-, β-, and γ-melanocyte-stimulating hormone (α-, β-, γ-MSH) and adrenocorticotropic hormone (ACTH), are elements of an ancient modulatory system. Natural melanocortins derive from the common precursor pro-opiomelanocortin (POMC). Five receptor subtypes for melanocortins (MC
A. Catania   +5 more
openaire   +4 more sources

Transcriptomic Signatures of Airway Epithelium Infected With SARS-CoV-2: A Balance Between Anti-infection and Virus Load

open access: yesFrontiers in Cell and Developmental Biology, 2021
COVID-19 pneumonia requires effective medical therapies. However, it is a challenge to find therapeutic drugs that not only inhibit viral replication, but also inhibit the accompanying cytokine storm and maintain an appropriate immune response.
Lingzhang Meng   +10 more
doaj   +1 more source

The complement receptor C5aR2 regulates neutrophil activation and function contributing to neutrophil-driven epidermolysis bullosa acquisita

open access: yesFrontiers in Immunology, 2023
IntroductionThe function of the second receptor for the complement cleavage product C5a, C5aR2, is poorly understood and often neglected in the immunological context.
Daniel L. Seiler   +13 more
doaj   +1 more source

Preoperative systemic inflammation predicts postoperative infectious complications in patients undergoing curative resection for colorectal cancer [PDF]

open access: yes, 2009
The presence of systemic inflammation before surgery, as evidenced by the glasgow prognostic score (mGPS), predicts poor long-term survival in colorectal cancer. The aim was to examine the relationship between the preoperative mGPS and the development of
Leitch, E.F.   +11 more
core   +1 more source

The B Cell Response and Formation of Allergenic and Anti-Allergenic Antibodies in Food Allergy

open access: yesBiology, 2023
Food allergies are a growing public health concern worldwide, especially in children and young adults. Allergen-specific IgE plays a central role in the pathogenesis of food allergies, but their titers poorly correlate with allergy development.
Christopher C. Udoye   +2 more
doaj   +1 more source

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