Results 51 to 60 of about 2,526,873 (311)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Emerging role of C5aR2: novel insights into the regulation of uterine immune cells during pregnancy
Frontiers in ImmunologyPregnancy is a fascinating immunological phenomenon because it allows allogeneic fetal and placental tissues to survive inside the mother. As a component of innate immunity with high inflammatory potential, the complement system must be tightly regulated
Fenna Froehlich +7 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Exploring the Boundaries of Systemic Inflammation* [PDF]
Critical Care Medicine, 2014 Understanding the mechanisms that limit or propagate tissue injury during systemic inflammation may provide the basis for preventing secondary organ dysfunction during serious infections. Endotoxin, an outer membrane component of gram-negative bacteria, is the archetypical microbial factor that mediates inflammation associated with these infections ...
Jason M, Elinoff, Anthony F, Suffredini
openaire +2 more sources
CellsAir–liquid interface (ALI) cultures offer a physiologically relevant in vitro model of the airway epithelium (AE), capable of recapitulating key structural and functional features observed in vivo. In this study, we established and validated a murine ALI
Janti Haj Ahmad +4 more
doaj +1 more source
F1000Research, 2013 Red blood cells (RBCs) from a rhesus D (RhD)-positive fetus that reach the bloodstream of an RhD-negative pregnant woman during birth can induce a pathogenic antibody (Ab) response against the RhD-positive RBCs, leading to fetal hemolytic disease in ...
André Winkler +2 more
doaj +1 more source
Causes of systemic inflammation.
, 2014 Causes of systemic inflammation.
Atsushi Umemura (158649) +7 more
core +1 more source
IMMUNOLOGICAL AND PATHOPHYSIOLOGICAL MECHANISMS OF SYSTEMIC INFLAMMATION [PDF]
, 2014 . The lecture presents modern data on systemic inflammation, as well as an original concept of its genesis. This disorder is considered a typical pathological process being fundamental to pathogenesis of the most critical states of different origin ...
E. Yu. Gusev, V. A. Chereshnev
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The heterogeneity of systemic inflammation in bronchiectasis [PDF]
Respiratory Medicine, 2017 Systemic inflammation in bronchiectasis is poorly studied in relation to aetiology and severity. We hypothesized that molecular patterns of inflammation may define particular aetiology and severity groups in bronchiectasis.We assayed blood concentrations of 31 proteins from 90 bronchiectasis patients (derivation cohort) and conducted PCA to examine ...
Saleh, Aarash D. +8 more
openaire +4 more sources