Results 31 to 40 of about 2,412,424 (259)

Complement Has Brains—Do Intracellular Complement and Immunometabolism Cooperate in Tissue Homeostasis and Behavior?

Frontiers in Immunology, 2021
The classical liver-derived and serum-effective complement system is well appreciated as a key mediator of host protection via instruction of innate and adaptive immunity.
Natalia Kunz, Claudia Kemper, Claudia Kemper   +2 more
doaj   +1 more source

ADAM-10 Regulates MMP-12 during Lipopolysaccharide-Induced Inflammatory Response in Macrophages

Journal of Immunology Research, 2022
A disintegrin and metalloprotease 10 (ADAM-10), a member of the ADAM protease family, has biological activities related to TNF-α activation, cell adhesion, and migration, among other functions.
Yan Jiang, Qiming Gong, Jinmei Huang, Yuanxun Gong, Qiang Tang, Dalong Wei, Qianli Tang, Jingjie Zhao, Jian Song, Lingzhang Meng   +9 more
doaj   +1 more source

S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells

Frontiers in Oncology, 2021
Multiple myeloma (MM) is a lethal hematological malignancy characterized by abundant myeloid cells in the microenvironment that fuel tumor progression. But the mechanism by which myeloid cells support myeloma cells has not been fully explored.
Lingzhang Meng, Lingzhang Meng, Qiang Tang, Jingjie Zhao, Zechen Wang, Liuzhi Wei, Liuzhi Wei, Qiuju Wei, Qiuju Wei, Lianfei Yin, Shiguan Luo, Jian Song, Jian Song   +12 more
doaj   +1 more source

Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis

Frontiers in Immunology, 2022
Clear cell renal cell carcinoma (ccRCC) usually affects multiple organs (e.g., bone and brain), and patient prognosis is usually poor. Although it is known that CD8+ T cell infiltration can potentially alleviate ccRCC progression, few studies have ...
Jie Wang, Jie Wang, Feifan Huang, Jingjie Zhao, Peng Huang, Junhua Tan, Meiying Huang, Ruiying Ma, Yu Xiao, Siyuan He, Zechen Wang, Jiajia Shen, Heming Lu, Lingzhang Meng, Lingzhang Meng   +14 more
doaj   +1 more source

Treatment of periodontitis and endothelial function [PDF]

, 2007
Background: Systemic inflammation may impair vascular function, and epidemiologic data suggest a possible link between periodontitis and cardiovascular disease.
Deanfield, John, Nibali, Luigi, Suvan, Jean, Vallance, Patrick, Storry, Clare, Nibali, L., Donald, Ann, D'Aiuto, F., Storry, C., Parkar, Mohamed, Vallance, P., Hingorani, A.D., Tonetti, Maurizio S., Parkar, M., Deanfield, J., Hingorani, Aroon D., Suvan, J., Donald, A., D'Aiuto, Francesco, Tonetti, M.S.   +19 more
core   +1 more source

A Novel Role for C5a in B-1 Cell Homeostasis

Frontiers in Immunology, 2018
B-1 cells constitute a unique subpopulation of lymphocytes residing mainly in body cavities like the peritoneal cavity (PerC) but are also found in spleen and bone marrow (BM).
Katharina Bröker, Julia Figge, Albert F. Magnusen, Rudolf A. Manz, Jörg Köhl, Jörg Köhl, Christian M. Karsten   +6 more
doaj   +1 more source

Human papillomavirus infection can alter the level of tumour stemness and T cell infiltration in patients with head and neck squamous cell carcinoma

Frontiers in Immunology, 2022
Head and neck squamous cell carcinoma (HNSCC) usually has a poor prognosis and is associated with a high mortality rate. Its etiology is mainly the result from long-term exposure to either alcohol, tobacco or human papillomavirus (HPV) infection or a ...
Lingzhang Meng, Lingzhang Meng, Heming Lu, Heming Lu, Yueyong Li, Jingjie Zhao, Siyuan He, Zechen Wang, Jiajia Shen, Huixian Huang, Huixian Huang, Jinru Xiao, Suren Rao Sooranna, Jian Song, Jian Song   +14 more
doaj   +1 more source

The role of inflammation, oxidative stress and the apolipoprotein E genotype in HIV-associated cognitive impairment: a clinical, biochemical and neuro-imaging study [PDF]

, 2010
Includes abstract.Includes bibliographical references (leaves 113-135).Twenty percent of HIV-infected patients develop HIV-associated neurocognitive disorders (HAND), a spectrum of neurological diseases which includes HIV-associated dementia (HAD), a ...
Mahne, Anna Cecilia
core   +1 more source

Role of adipose tissue as an endocrineorgan in systemic inflammation [PDF]

, 2014
Introduction The escalating public health problem represented by obesity has spurred multidisciplinary research into adipose tissue and importantly, the molecular biology of the adipocyte.
Kosicka, A.
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source