Results 21 to 30 of about 66,314 (265)

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice

Haematologica, 2016
Systemic mastocytosis is a heterogeneous disease characterized by the accumulation of neoplastic mast cells in the bone marrow and other organ organs/tissues.
Celalettin Ustun, Michel Arock, Hanneke C. Kluin-Nelemans, Andreas Reiter, Wolfgang R. Sperr, Tracy George, Hans-Peter Horny, Karin Hartmann, Karl Sotlar, Gandhi Damaj, Olivier Hermine, Srdan Verstovsek, Dean D. Metcalfe, Jason Gotlib, Cem Akin, Peter Valent   +15 more
doaj   +1 more source

KITD816V+ systemic mastocytosis associated with KITD816V+ acute erythroid leukaemia: first case report with molecular evidence for same progenitor cell derivation [PDF]

, 2009
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
H-P Horny, K K Reichard, K Sotlar, M K Foucar, S A McClintock-Treep   +4 more
core   +1 more source

Cytology of systemic mastocytosis [PDF]

American Journal of Hematology, 2009
Cytology of systemic ...
Alexandra J. Marks, Barbara J. Bain
openaire   +3 more sources

Cephalalgia against the background of systemic mastocytosis: a clinical case

Бюллетень сибирской медицины, 2021
The article presents a clinical case of comorbid pathology – development of migraine against the background of systemic mastocytosis. The classification and clinical manifestations of systemic mastocytosis, a rare blood disease, are given.This clinical ...
P. I. Kuznetsova, M. M. Tanashyan, A. L. Melikyan, I. N. Subortseva, A. A. Raskurazhev   +4 more
doaj   +1 more source

Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3. [PDF]

, 2008
Systemic mastocytoses represent neoplastic proliferations of mast cells. In about 20% of cases systemic mastocytoses are accompanied by clonal haematopoietic non-mast cell-lineage disorders, most commonly myeloid neoplasms.
Dirnhofer, S., Horny, H.-P., Jotterand, M., Muhlematter, D., Sotlar, Karl, Theocharides, A., Tzankov, A., Went, P.   +7 more
core   +1 more source

Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]

, 2008
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
B. Przybilla, D. Fritze, Dubois AE, F. Ruëff, Fricker M, Ludolph-Hauser D, M. Hagedorn, N. Wagner, Reimers A, Rueff F   +9 more
core   +1 more source

A unique presentation of pulmonary disease in advanced systemic mastocytosis, proven by the presence of mast cells in bronchoalveolar lavage: A case report [PDF]

, 2016
Background: Systemic mastocytosis is a rare myeloproliferative disease characterized by the uncontrolled proliferation of aberrant mast cells. It has varying clinical manifestations.
Broijl, A. (Annemiek), Daele, P.L.A. (Paul) van, Hermans, M.A.W. (Maud A.W.)   +2 more
core   +2 more sources

Diffuse cutaneous mastocytosis with novel somatic KIT mutation K509I and association with tuberous sclerosis. [PDF]

, 2018
Diffuse cutaneous mastocytosis (DCM) is a rare but potentially fatal condition when diagnosis and targeted treatments are delayed. This case illustrates the life-threatening complications in DCM and reviews the currently available treatments.
Akin, Alvarez-Twose, Bankova, Bodemer, Brockow, Brockow, Caughey, Chan, Edwards, Escribano, Escribano, Flageul, Fried, Galli, Garg, Hannaford, Hartmann, Has, Heide, Huang, Lange, Melo, Murphy, Orkin, Polk, Poterack, Prieto-García, Smith, Tolar, Valent, Wolff, Zhang, Álvarez-Twose   +32 more
core   +1 more source

SYSTEMIC MASTOCYTOSIS: MULTIDISCIPLINARY APPROACH

Mediterranean Journal of Hematology and Infectious Diseases, 2021
Systemic mastocytosis (SM) is a heterogeneous group of diseases that affect almost exclusively adults and are defined by the proliferation and accumulation of clonal mast cells (MC) in various tissues. Disease subtypes range from indolent to rare but aggressive forms.
Giovanni Orsolini, Patrizia Bonadonna, Roberta Zanotti, Donatella Schena, Lara Crosera, Francesca Mastropaolo, Massimiliano Bonifacio, Elisa Olivieri, Ilaria Tanasi, Morena Tebaldi   +9 more
openaire   +5 more sources

Biochemical markers predictive for bone marrow involvement in systemic mastocytosis

Haematologica, 2008
Systemic mastocytosis is characterized by bone marrow involvement, which requires a bone marrow biopsy for diagnostic work-up. We questioned whether bone marrow involvement could be predicted using biochemical markers.
Marjolein L. Donker, Jasper J. van Doormaal, Frederiek F. van Doormaal, Philip M. Kluin, Eveline van der Veer, Jan G.R. de Monchy, Ido P. Kema, Hanneke C. Kluin-Nelemans   +7 more
doaj   +1 more source