Results 11 to 20 of about 68,714 (217)

How “benign” is cutaneous mastocytosis? A Danish registry-based matched cohort study

International Journal of Women's Dermatology, 2020
Background: There are limited estimates of the incidence rates (IRs) of mastocytosis, and only a few studies have addressed the long-term consequences of living with these diagnoses.
Line Kibsgaard, MD, PhD, Mette Deleuran, MD, Head of Department, Carsten Flohr, MD, Head of Department, Sinéad Langan, MD, Anne Braae Olesen, MD, PhD, Christian Vestergaard, MD, PhD   +5 more
doaj   +1 more source

Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report

International Journal of Dermatology and Venerology, 2023
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason, Volkan Tekmen, Alexa Cohen, Safiyyah Bhatti, Burcu Beksac, Jisun Cha, Pierluigi Porcu, Neda Nikbakht   +7 more
doaj   +1 more source

Urticaria pigmentosa and systemic mastocytosis

Clinical Case Reports, 2023
Key Clinical Message Additional investigations for systemic involvement should be initiated once the diagnosis of cutaneous mastocytosis has been established in an adult patient.
Jonathan Keow, Benjamin Chin‐Yee, Cyrus C. Hsia, Kara Robertson   +3 more
doaj   +1 more source

Cephalalgia against the background of systemic mastocytosis: a clinical case

Бюллетень сибирской медицины, 2021
The article presents a clinical case of comorbid pathology – development of migraine against the background of systemic mastocytosis. The classification and clinical manifestations of systemic mastocytosis, a rare blood disease, are given.This clinical ...
P. I. Kuznetsova, M. M. Tanashyan, A. L. Melikyan, I. N. Subortseva, A. A. Raskurazhev   +4 more
doaj   +1 more source

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice

Haematologica, 2016
Systemic mastocytosis is a heterogeneous disease characterized by the accumulation of neoplastic mast cells in the bone marrow and other organ organs/tissues.
Celalettin Ustun, Michel Arock, Hanneke C. Kluin-Nelemans, Andreas Reiter, Wolfgang R. Sperr, Tracy George, Hans-Peter Horny, Karin Hartmann, Karl Sotlar, Gandhi Damaj, Olivier Hermine, Srdan Verstovsek, Dean D. Metcalfe, Jason Gotlib, Cem Akin, Peter Valent   +15 more
doaj   +1 more source

Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]

, 2010
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
core   +1 more source

KITD816V+ systemic mastocytosis associated with KITD816V+ acute erythroid leukaemia: first case report with molecular evidence for same progenitor cell derivation [PDF]

, 2009
Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
H-P Horny, K K Reichard, K Sotlar, M K Foucar, S A McClintock-Treep   +4 more
core   +1 more source

Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]

, 2008
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
B. Przybilla, D. Fritze, Dubois AE, F. Ruëff, Fricker M, Ludolph-Hauser D, M. Hagedorn, N. Wagner, Reimers A, Rueff F   +9 more
core   +1 more source

Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis [PDF]

, 2016
Neoplastic accumulation of mast cells in systemic mastocytosis (SM) associates with activating mutations in the receptor tyrosine kinase KIT. Constitutive activation of tyrosine kinase oncogenes has been linked to imbalances in oxidant/antioxidant ...
Bai, Yun, Bandara, Geethani, Beaven, Michael A., Desai, Avanti, Kim, Do-Kyun, Komarow, Hirsh, Kulinski, Joseph M., Metcalfe, Dean D., Olivera, Ana, Prussin, Calman, Schwartz, Lawrence B.   +10 more
core   +9 more sources

A unique presentation of pulmonary disease in advanced systemic mastocytosis, proven by the presence of mast cells in bronchoalveolar lavage: A case report [PDF]

, 2016
Background: Systemic mastocytosis is a rare myeloproliferative disease characterized by the uncontrolled proliferation of aberrant mast cells. It has varying clinical manifestations.
Broijl, A. (Annemiek), Daele, P.L.A. (Paul) van, Hermans, M.A.W. (Maud A.W.)   +2 more
core   +2 more sources