Results 11 to 20 of about 978,166 (202)
CD30 in Systemic Mastocytosis [PDF]
Immunology and Allergy Clinics of North America, 2014 CD30 is a transmembrane receptor, normally not expressed by mast cells, which regulates proliferation/apoptosis and antibody responses. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis.
van Anrooij, Bjorn +3 more
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Biochemical markers predictive for bone marrow involvement in systemic mastocytosis [PDF]
Haematologica, 2008 Systemic mastocytosis is characterized by bone marrow involvement, which requires a bone marrow biopsy for diagnostic work-up. We questioned whether bone marrow involvement could be predicted using biochemical markers.
Marjolein L. Donker +7 more
doaj +2 more sources
Hematology/Oncology Clinics of North America, 2010 An unusual disease, mastocytosis challenges the pathologist with a variety of morphologic appearances and heterogeneous clinical presentations ranging from skin manifestations (pruritus, urticaria, dermatographism) to systemic signs and symptoms indicative of mast cell mediator release, including flushing, hypotension, headache, and anaphylaxis among ...
Tracy I, George, Hans-Peter, Horny
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Urticaria pigmentosa and systemic mastocytosis [PDF]
Clinical Case Reports, 2023 Key Clinical Message Additional investigations for systemic involvement should be initiated once the diagnosis of cutaneous mastocytosis has been established in an adult patient.
Jonathan Keow +3 more
doaj +5 more sources
Review papers The role of KIT gene mutations in pathogenesis of pediatric mastocytosis
Przegląd Dermatologiczny, 2015 Mastocytosis is characterized by excessive proliferation and accumulation of mast cells in skin and/or other organs. Two forms of the disease, cutaneous and systemic mastocytosis, differ significantly in symptomatology and clinical course.
Joanna Dawicka +5 more
doaj +2 more sources
Blood, 2013 The term mastocytosis encompasses a heterogeneous group of clonal diseases characterized by proliferation and accumulation of mast cells (MC) in different tissues, mainly skin and bone marrow (BM).
Bouvier, Sylvie, Arnaud, Anne
core +6 more sources
Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice [PDF]
Haematologica, 2016 Systemic mastocytosis is a heterogeneous disease characterized by the accumulation of neoplastic mast cells in the bone marrow and other organ organs/tissues.
Celalettin Ustun +15 more
doaj +2 more sources
Diffuse large B cell lymphoma coexistence with systemic mastocytosis
Journal of Cancer Research and Practice, 2016 Systemic mastocytosis is a rare disease and characterized by excessive mast cell accumulation in one or multiple organs. One subtype of systemic mastocytosis is systemic mastocytosis-associated clonal hematological non-mast cell lineage disease (SM-AHMND)
Sheng-Hsuan Chien +8 more
doaj +2 more sources
Multiple large osteolytic lesions in a patient with systemic mastocytosis: a challenging diagnosis [PDF]
Clinical Case Reports, 2017 Key Clinical Message Patients with advanced variants of Systemic Mastocytosis may develop destructive bone lesions when massive mast cell (MC) infiltrates are present. Finding of large osteolyses in indolent systemic mastocytosis, typically characterized
Massimiliano Bonifacio +14 more
doaj +2 more sources
, 2015 A 64-year-old man was admitted to the hematology ward due to neutropenia and thrombocytopenia. The only symptom in the month preceding his admission, was significant weight loss.
Rontogianni, Dimitra +5 more
openaire +2 more sources