Increased TIM-3 and GAL-9 serum levels in patients with advanced systemic mastocytosis. [PDF]
BACKGROUND Systemic mastocytosis is characterized by expansion of clonal mast cells in various tissues. Several biomarkers with diagnostic and therapeutic potential have recently been characterized in mastocytosis, such as the serum marker tryptase ...
Peter Valent +19 more
core +3 more sources
Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma
A patient with a history of non-diagnostic bone marrow biopsies presented with a red to brown maculopapular rash on the back. Biopsies confirmed multiple xanthogranulomas as well as a mastocytosis.
Philipp Tschandl +2 more
doaj +1 more source
Adult-onset mastocytosis in the skin is highly suggestive of systemic mastocytosis [PDF]
Adult-onset urticaria pigmentosa/mastocytosis in the skin almost always persists throughout life. The prevalence of systemic mastocytosis in such patients is not precisely known. Bone marrow biopsies from 59 patients with mastocytosis in the skin and all
Flaig, Michael J. +9 more
core +2 more sources
Systemic mastocytosis in the elderly [PDF]
“Later onset” of systemic mastocytosis (SM) has been associated with a poorer prognosis. We examined clinical and laboratory findings, associated disorders, and survival in an older mastocytosis population. After receiving Mayo Clinic Institutional Review Board approval, we identified 42 patients aged 70 years and older at the time of diagnosis of SM ...
Joseph H, Butterfield +1 more
openaire +2 more sources
KIT mutation analysis in mast cell neoplasms: recommendations of the European competence network on mastocytosis [PDF]
Although acquired mutations in KIT are commonly detected in various categories of mastocytosis, the methodologies applied to detect and quantify the mutant type and allele burden in cells and various tissues are poorly defined.
T. Haferlach +79 more
core +1 more source
Cephalalgia against the background of systemic mastocytosis: a clinical case
The article presents a clinical case of comorbid pathology – development of migraine against the background of systemic mastocytosis. The classification and clinical manifestations of systemic mastocytosis, a rare blood disease, are given.This clinical ...
P. I. Kuznetsova +4 more
doaj +1 more source
Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
Rueff, F. +4 more
core +1 more source
Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P. +5 more
core +1 more source
Evaluation of Mast Cell Activation Syndromes: Impact of Pathology and Immunohistology [PDF]
Mast cell activation syndromes (MCAS) are clinically defined disease states with a largely unknown morphological background. Since mastocytosis may be associated with MCAS, it is crucial in every patient to document or exclude mastocytosis by appropriate
Horny, H. -P., Valent, P., Sotlar, K.
core +1 more source
Adult mastocytosis: a review of the Santo António Hospital 's experience and an evaluation of World Health Organization criteria for the diagnosis of systemic disease [PDF]
BACKGROUND: Mastocytosis is a clonal disorder characterized by the accumulation of abnormal mast cells in the skin and/or in extracutaneous organs. OBJECTIVES: To present all cases of mastocytosis seen in the Porto Hospital Center and evaluate the ...
Iolanda Conde Fernandes +5 more
doaj +1 more source

