Results 31 to 40 of about 706,908 (282)
Causal Inference using Multivariate Generalized Linear Mixed-Effects Models with Longitudinal Data [PDF]
arXiv, 2023 Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes and treatment assignment mechanisms are unknown in observational studies, an individual's treatment efficacy is a ...
arxiv
Control of Fibrosis in Systemic Scleroderma.
Journal of Investigative Dermatology, 1993 Scleroderma is characterized by an excessive deposition of collagen in all involved organs. This is due to an overproduction of extracellular matrix (ECM) molecules following induction of gene expression, whereas there is no evidence that the composition of the connective tissue matrix is altered.
Cornelia Mauch +5 more
openaire +3 more sources
Scleroderma and scleroderma-like syndromes
Frontiers in ImmunologySystemic sclerosis is a systemic connective tissue disease whose main pathophysiological mechanism is a progressive fibrosis of internal organs and skin leading to thickening and induration. Blood vessels may also be involved.
Katarzyna Romanowska-Próchnicka +4 more
doaj +1 more source
Localized Scleroderma, Systemic Sclerosis and Cardiovascular Risk: A Danish Nationwide Cohort Study
Acta Dermato-Venereologica, 2017 Recent findings indicate that patients with systemic sclerosis have an increased risk of cardiovascular disease. To determine whether patients with systemic sclerosis or localized scleroderma are at increased risk of cardiovascular disease, a cohort ...
Jeanette Halskou Hesselvig +5 more
doaj +1 more source
Central retinal vein occlusion: A patient with systemic sclerosis [PDF]
Vojnosanitetski Pregled, 2016 Introduction. Scleroderma (systemic sclerosis) is a severe chronic connective tissue disease, which results in involvement of numerous internal organs.
Karadžić Jelena +2 more
doaj +1 more source
SCLERODERMA NEPHROPATHY: UNSOLVED PROBLEMS
Juvenis Scientia, 2021 Kidney injury is a common pathology in the group of patients with systemic sclerosis. At least half of the patients show histological signs of it. Acute condition is known as scleroderma renal crisis.
I. E. Bulavko +3 more
doaj +1 more source
Systemic sclerosis sine scleroderma [PDF]
Advances in Clinical and Experimental Medicine, 2017 Systemic sclerosis is a rare generalized disease with scleroderma, i.e. skin thickening as one of the most common symptoms. The disease has 2 main subsets, diffuse and limited forms. The subset known as systemic sclerosis sine scleroderma (ssSSc) is a very rare subset characterized by the total or partial absence of cutaneous manifestations of systemic
Magdalena Kopeć-Mędrek +1 more
openaire +3 more sources
Pathophysiology of systemic sclerosis (scleroderma)
The Kaohsiung Journal of Medical Sciences, 2022 AbstractSystemic sclerosis (scleroderma) is an autoimmune‐triggered chronic fibrosing disease that affects the skin and many other organs. Its pathophysiology is complex and involves an early endothelial damage, an inflammatory infiltrate and a resulting fibrotic reaction.
Ann‐Helen Rosendahl +2 more
openaire +3 more sources
Современная ревматология, 2013 Systemic connective tissue diseases, systemic scleroderma in particular, constitute a group of diseases in which vascular disorders underlying diverse clinical manifestations are one of the pathogenetic components.
Aleksandr Vitalyevich Volkov +1 more
doaj +1 more source
Immunologic and nonimmunologic sclerodermal skin conditions - review
Frontiers in Immunology, 2023 Scleroderma-like cutaneous lesions have been found in many pathological conditions and they have the clinical appearance of sclerotic or scleroatrophic lesions.
Carmen Bobeica +17 more
doaj +1 more source