Results 261 to 270 of about 307,381 (359)

Assessment of New Inflammatory Indexes in Systemic Sclerosis with Interstitial Lung Disease. [PDF]

Eurasian J Med
Ecesoy V, Ecesoy H.
europepmc   +1 more source

Exposure to occupational inhalants and the risk of developing rheumatoid arthritis: A systematic review and meta‐analysis

Arthritis &Rheumatology, Accepted Article.
Objective: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint pain, swelling, and stiffness. While smoking is a well‐established risk factor for RA, the role of occupational inhalants in RA development is less well recognized.
Qianwen Liu, Xin Song, Emily Mauro, Yuan Jiang, Klementy Shchetynsky, PLars Klareskog, Lars Alfredsson, Xia Jiang   +7 more
wiley   +1 more source

Advances in the Molecular Mechanisms of Pulmonary Fibrosis in Systemic Sclerosis: A Comprehensive Review. [PDF]

Int J Mol Sci
Alcolea MPI, Starita Fajardo G, Peña Rodríguez M, Lucena López D, Suárez Carantoña C, López Paraja M, García de Vicente A, Viteri-Noël A, González García A.   +8 more
europepmc   +1 more source

Population pharmacokinetic modelling revealed large variability in oromucosal absorption of Δ9‐tetrahydrocannabinol in older patients with poor appetite

British Journal of Clinical Pharmacology, EarlyView.
Aim Cannabis‐based medicines are gaining interest and being explored for new therapeutic indications, many of which commonly affect older medical patients. As most previous studies of the population pharmacokinetics of cannabinoids have been performed in healthy adults, this study aimed to investigate the population pharmacokinetics of Δ9 ...
Ida Klitzing Storgaard, Rikke Lundsgaard Nielsen, Morten Baltzer Houlind, Olivia Bornæs, Louise Westberg Strejby Christensen, Aino Leegaard Andersen, Helle Gybel Juul‐Larsen, Lillian Mørch Jørgensen, Torben Breindahl, Baker Nawfal Jawad, Izzet Altintas, Ove Andersen, Trine Meldgaard Lund   +12 more
wiley   +1 more source

Sexual Dysfunction Is Common in Reproductive-Age Women with Systemic Sclerosis. [PDF]

Life (Basel)
Salang L, Buppasiri P, Jutiviboonsuk A, Foocharoen C.   +3 more
europepmc   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Characteristics of patients with systemic sclerosis with aspiration: A single-center study. [PDF]

J Scleroderma Relat Disord
Naganawa T, Hashimoto T, Ikeda N, Takase H, Dosoden N, Ito K, Sawada M, Ito Y, Watanabe N, Umeda A, Akamatsu K, Kurumizawa M, Nishino J, Fukaya S, Inamoto Y, Shibata S, Otaka Y, Yasuoka H.   +17 more
europepmc   +1 more source

Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat

British Journal of Clinical Pharmacology, EarlyView.
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton, Nielka P. van Erp, Annenienke C. van de Ven, Janneke E. W. Walraven, Loek A. W. de Jong   +4 more
wiley   +1 more source

Scleroderma Clinical Trials Consortium Classification Criteria for Systemic Sclerosis Heart Involvement

Ross L, Burns AT, La Gerche A, Hansen D, Coghlan JG, Stevens W, Prior D, Pham A, McKelvie P, Bellocchi C, Braun Moscovici Y, Bruni C, Carreira P, Frech T, Hoa S, Hudson M, Hsu V, Low AHL, Matucci-Cerinic M, Medina Fonseca B, Ng S, Rodriguez Reyna T, Sahhar J, Talaat M, Proudman S, Vacca A, Baron M, Nikpour M.   +27 more
europepmc   +1 more source