Results 271 to 280 of about 307,381 (359)

A screening tool to detect interstitial lung disease in systemic sclerosis: the ILD-RISC score. [PDF]

open access: yesRheumatology (Oxford)
Bruni C   +15 more
europepmc   +1 more source

Delivery strategies of messenger RNA therapeutics for brain disorders

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Thus, mRNA therapeutics offer a powerful new avenue for the treatment of brain diseases. This review examines strategies to bypass biological barriers, particularly the blood–brain barrier, and explores emerging delivery systems, such as direct intracerebral injection, intracerebroventricular injection, systemic delivery (including intravenous ...
Kounghwa Youn   +5 more
wiley   +1 more source

Sex differences in systemic sclerosis: from pathogenesis to clinical manifestations and treatment. [PDF]

open access: yesTher Adv Musculoskelet Dis
Toitou M   +7 more
europepmc   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

Systemic Sclerosis: A Key Model of Endothelial Dysfunction. [PDF]

open access: yesBiomedicines
Zaccone V   +5 more
europepmc   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

open access: yesBMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo   +9 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

Criteria for defining and dating onset of organ system involvement in systemic sclerosis. [PDF]

open access: yesJ Scleroderma Relat Disord
Hudson M   +10 more
europepmc   +1 more source

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