Systemic sclerosis and risk of bronchiectasis: a nationwide longitudinal cohort study
Background The association between systemic sclerosis and the development of bronchiectasis is unclear. This study aimed to compare the risk of bronchiectasis between individuals with systemic sclerosis and those without using a nationwide longitudinal ...
Bumhee Yang+11 more
doaj +1 more source
Predictors of fatigue severity in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort. [PDF]
ObjectivesLongitudinal studies examining the baseline predictors of fatigue in SSc have not been reported. Our objectives were to examine the course of fatigue severity over time and to identify baseline clinical, demographic, and psychosocial predictors
Assassi, Shervin+10 more
core +19 more sources
Living with Systemic Sclerosis: A Patient and Physician Perspective
The fears associated with being diagnosed with a disease unfamiliar to many, systemic sclerosis, is described by a patient living with systemic sclerosis.
Arissa Young+2 more
doaj +1 more source
Pulmonary hypertension phenotypes in patients with systemic sclerosis
Pulmonary hypertension (PH) commonly affects patients with systemic sclerosis (SSc) and is associated with significant morbidity and increased mortality.
A. Haque+4 more
semanticscholar +1 more source
Systemic sclerosis is a complex autoimmune connective tissue disease which carries a significant burden of disease-related morbidity including potentially life-threatening complications. Systemic sclerosis can affect all the major organs and therefore, although the disease is uncommon, many hospital-based specialists are involved in patient care ...
Hughes, Michael, Herrick, Ariane L
openaire +7 more sources
A Case Report of Systemic Sclerosis Complicated by Biventricular Heart Failure, Pulmonary Hypertension and Review of Literature [PDF]
Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disorder whose aetiology is not fully understood. Skin fibrosis and visceral organs involvement are the hallmarks, and the heart could be disproportionately or subtly involved ...
Akinboro AO+3 more
core +1 more source
α2-Antiplasmin as a Potential Therapeutic Target for Systemic Sclerosis
Systemic sclerosis is a connective tissue disease of unknown origin that is characterized by immune system abnormalities, vascular damage, and extensive fibrosis of the skin and visceral organs.
Yosuke Kanno, En Shu
doaj +1 more source
Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core +2 more sources
Predictors of progression in systemic sclerosis patients with interstitial lung disease
Systemic sclerosis (SSc) is a systemic autoimmune disease affecting multiple organ systems, including the lungs. Interstitial lung disease (ILD) is the leading cause of death in SSc.
O. Distler+12 more
semanticscholar +1 more source
Connective tissue disease-associated pulmonary arterial hypertension. [PDF]
Although rare in its idiopathic form, pulmonary arterial hypertension (PAH) is not uncommon in association with various associated medical conditions, most notably connective tissue disease (CTD).
Condliffe, R., Howard, L.S.
core +2 more sources