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The Lancet, 2017 Systemic sclerosis, also called scleroderma, is an immune-mediated rheumatic disease that is characterised by fibrosis of the skin and internal organs and vasculopathy. Although systemic sclerosis is uncommon, it has a high morbidity and mortality. Improved understanding of systemic sclerosis has allowed better management of the disease, including ...
Denton, CP, Khanna, D
openaire +5 more sources
Systemic sclerosis and risk of bronchiectasis: a nationwide longitudinal cohort study
Arthritis Research & Therapy, 2023 Background The association between systemic sclerosis and the development of bronchiectasis is unclear. This study aimed to compare the risk of bronchiectasis between individuals with systemic sclerosis and those without using a nationwide longitudinal ...
Bumhee Yang +11 more
doaj +1 more source
Living with Systemic Sclerosis: A Patient and Physician Perspective
Rheumatology and Therapy, 2023 The fears associated with being diagnosed with a disease unfamiliar to many, systemic sclerosis, is described by a patient living with systemic sclerosis.
Arissa Young +2 more
doaj +1 more source
Pulmonary hypertension phenotypes in patients with systemic sclerosis
European Respiratory Review, 2021 Pulmonary hypertension (PH) commonly affects patients with systemic sclerosis (SSc) and is associated with significant morbidity and increased mortality.
A. Haque +4 more
semanticscholar +1 more source
British Journal of Hospital Medicine, 2019 Systemic sclerosis is a complex autoimmune connective tissue disease which carries a significant burden of disease-related morbidity including potentially life-threatening complications. Systemic sclerosis can affect all the major organs and therefore, although the disease is uncommon, many hospital-based specialists are involved in patient care ...
Hughes, Michael, Herrick, Ariane L
openaire +7 more sources
α2-Antiplasmin as a Potential Therapeutic Target for Systemic Sclerosis
Life, 2022 Systemic sclerosis is a connective tissue disease of unknown origin that is characterized by immune system abnormalities, vascular damage, and extensive fibrosis of the skin and visceral organs.
Yosuke Kanno, En Shu
doaj +1 more source
Effectiveness of regional diffusion MRI measures in distinguishing multiple sclerosis abnormalities within the cervical spinal cord [PDF]
, 2021 Multiple sclerosis is an inflammatory disorder of the central nervous system. Quantitative MRI has huge potential to provide intrinsic and normative values of tissue properties useful for diagnosis, prognosis and ultimately clinical follow-up of this disease.
arxiv +1 more source
Predictors of progression in systemic sclerosis patients with interstitial lung disease
European Respiratory Journal, 2020 Systemic sclerosis (SSc) is a systemic autoimmune disease affecting multiple organ systems, including the lungs. Interstitial lung disease (ILD) is the leading cause of death in SSc.
O. Distler +12 more
semanticscholar +1 more source
Reaction-diffusion systems derived from kinetic theory for Multiple Sclerosis [PDF]
, 2023 We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both interactions among different populations of human cells and the motion of immune cells, stimulated by cytokines.
arxiv +1 more source
Annals of the Rheumatic Diseases, 2013 Objective The 1980 American College of Rheumatology (ACR) classification criteria for systemic sclerosis (SSc) lack sensitivity for early SSc and limited cutaneous SSc.
F. V. D. van den Hoogen +43 more
semanticscholar +1 more source