Results 291 to 300 of about 1,679,247 (398)

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Psychosomatic profile in patients with systemic sclerosis: results from an observational study. [PDF]

open access: yesFront Med (Lausanne)
Romanazzo S   +5 more
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Prostaglandin E1 restores endothelial progenitor cell function in systemic sclerosis. [PDF]

open access: yesRheumatology (Oxford)
Potjewijd J   +5 more
europepmc   +1 more source

Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8

open access: yesScience Translational Medicine, 2018
Marie Dominique Ah Kioon   +7 more
semanticscholar   +1 more source

The Failure Rate of Internal Fixation Increases With Sagittal Displacement of the Femoral Head: A Retrospective Study

open access: yesHealth Care Science, EarlyView.
This study found that the degree of femoral head sagittal displacement is linked to the risk of internal fixation failure in femoral neck fracture. Measurements of the sagittal tilt angle of the femoral head (STAFH) using CT‐3D imaging showed high reliability (ICC = 0.97, 95% CI: 0.96–0.98). Patients with excessive sagittal displacement (anterior tilt ≥
Lei Shi   +7 more
wiley   +1 more source

Inhaled Iloprost for Digital Necrosis in Systemic Sclerosis - An Effective Alternative. [PDF]

open access: yesEur J Case Rep Intern Med
Yousfi J   +6 more
europepmc   +1 more source

Ultrasonographic evaluation of hand and wrist joints in patients with systemic sclerosis. [PDF]

open access: yesJ Scleroderma Relat Disord
Ermancık Z   +7 more
europepmc   +1 more source

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