Results 31 to 40 of about 1,674,118 (394)

Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]

, 2006
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Evaluation of the primary biliary cholangitis-related serologic profile in a large cohort of Belgian systemic sclerosis patients [PDF]

, 2020
Background: Systemic sclerosis (SSc) and primary biliary cholangitis (PBC) are autoimmune diseases that may occur concomitantly and are both strongly associated with disease-specific autoantibodies.
Bonroy, Carolien, De Keyser, Filip, Devreese, Katrien, Florin, Lisa, Rubben, Kaat, Smith, Vanessa, Vanhaecke, Amber   +6 more
core   +1 more source

Predictors of progression in systemic sclerosis patients with interstitial lung disease

European Respiratory Journal, 2020
Systemic sclerosis (SSc) is a systemic autoimmune disease affecting multiple organ systems, including the lungs. Interstitial lung disease (ILD) is the leading cause of death in SSc.
O. Distler, S. Assassi, V. Cottin, M. Cutolo, S. Danoff, C. Denton, J. Distler, A. Hoffmann-Vold, S. Johnson, U. Müller Ladner, V. Smith, E. Volkmann, T. Maher   +12 more
semanticscholar   +1 more source

A Case Report of Systemic Sclerosis Complicated by Biventricular Heart Failure, Pulmonary Hypertension and Review of Literature [PDF]

, 2017
Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disorder whose aetiology is not fully understood. Skin fibrosis and visceral organs involvement are the hallmarks, and the heart could be disproportionately or subtly involved ...
Akinboro AO, Akinlade M, Akintunde AA, Audu MB   +3 more
core   +1 more source

Preventing Malnutrition through Adequate Management of Gastrointestinal Dysmotility in Systemic Sclerosis Patients: A Literature Review

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2023
Gastrointestinal dysmotility in systemic sclerosis occurs as the end result of extensive fibrosis of the gastrointestinal tract. The entire length of the tract from the esophagus to the anorectum could be affected, exerting various gastrointestinal ...
Eka Benhardi Layadi, Rabbinu Rangga Pribadi, Maria Teressa, Felicia Suharja, Oemar Ichsan   +4 more
doaj   +1 more source

Using Autoantibodies and Cutaneous Subset to Develop Outcome‐Based Disease Classification in Systemic Sclerosis

Arthritis & Rheumatology, 2020
To describe the associations between autoantibodies, clinical presentation, and outcomes among patients with systemic sclerosis (SSc) in order to develop a novel SSc classification scheme that would incorporate both antibodies and the cutaneous disease ...
S. Nihtyanova, A. Sarı, J. Harvey, A. Leslie, E. Derrett-Smith, C. Fonseca, V. Ong, C. Denton   +7 more
semanticscholar   +1 more source

Connective tissue disease-associated pulmonary arterial hypertension. [PDF]

, 2015
Although rare in its idiopathic form, pulmonary arterial hypertension (PAH) is not uncommon in association with various associated medical conditions, most notably connective tissue disease (CTD).
Condliffe, R., Howard, L.S.
core   +2 more sources

Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator‐Initiated, Multicenter, Double‐Blind, Randomized, Placebo‐Controlled Trial

Arthritis & Rheumatology, 2020
T cells play a key role in the pathogenesis of early systemic sclerosis. This study was undertaken to assess the safety and efficacy of abatacept in patients with diffuse cutaneous systemic sclerosis (dcSSc).
D. Khanna, C. Spino, S. Johnson, L. Chung, M. Whitfield, C. Denton, V. Berrocal, Jennifer M. Franks, B. Mehta, J. Molitor, V. Steen, R. Lafyatis, R. Simms, Anna Gill, S. Kafaja, T. Frech, V. Hsu, R. Domsic, J. Pope, J. Gordon, M. Mayes, E. Schiopu, A. Young, N. Sandorfi, Jane Park, F. Hant, E. Bernstein, S. Chatterjee, F. Castelino, A. Ajam, Yue Wang, Tammara A. Wood, Y. Allanore, M. Matucci-Cerinic, O. Distler, Ora Singer, Erica Bush, D. Fox, D. Furst   +38 more
semanticscholar   +1 more source

QTc interval prolongation in systemic sclerosis [PDF]

, 2017
QTc interval prolongation in systemic ...
Gigante, Antonietta, Rosato, Edoardo, Tubani, Luigi   +2 more
core   +1 more source

Spinal anesthesia for cesarean section in a patient with systemic sclerosis associated interstitial lung disease: a case report [PDF]

Korean Journal of Anesthesiology, 2016
Systemic sclerosis or scleroderma is a rare autoimmune disorder characterized by excessive fibrosis and, vasculopathy, with multiorgan involvement. Anesthetic considerations in patients with systemic sclerosis must take into account the degree of organ ...
Guie Yong Lee, Sooyoung Cho
doaj   +1 more source