Results 51 to 60 of about 311,988 (356)

Systemic Sclerosis and Cancer [PDF]

International Journal of Immunopathology and Pharmacology, 2009
To review recent advances and current controversies on the association between systemic sclerosis (SSc) and cancer, PUBMED was searched from 1966 to the present using the terms: systemic sclerosis, cancer, morphoea, sclerotic diseases. Malignancies, mainly in lung and breast, coexist with idiopathic SSc or with SSc-like disorders, but not with ...
Laura Belloli, Luisa Conciato, Marco Massarotti, Bianca Marasini   +3 more
openaire   +4 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Myocardial Involvement in a Patient with Systemic Sclerosis

Journal of Clinical Rheumatology and Immunology
Myocarditis is an uncommon presentation in systemic sclerosis. We report the case of a patient who developed myocarditis on the initial diagnosis of systemic sclerosis and was successfully managed with optimal medical treatment, including ...
Chris Ching Lam Cheung, Wan Man Choi
doaj   +1 more source

Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung disease [PDF]

, 2016
Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung ...
Amoroso, Daria, Barbano, Biagio, DI PAOLO, Marcello, Gigante, Antonietta, Palange, Paolo, Romaniello, Antonella, Rosato, Edoardo, Tallerini, Gaia   +7 more
core   +1 more source

Systemic Sclerosis 2011

International Journal of Rheumatology, 2011
Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by widespread fibrosis affecting the skin, internal organs, and vasculature. However, there are currently no systemic, disease-modifying therapies available for the treatment of the overall condition, and the outcomes remain poor.
Chung, Lorinda, Distler, Oliver, Hummers, Laura, Krishnan, Eswar, Steen, Virginia   +4 more
openaire   +2 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Aortic Regurgitation in a Patient with Rheumatoid Arthritis/Systemic Lupus Erythematosus Overlap Syndrome (Rhupus): Case Report and Review of Literature

Journal of Cardiovascular Development and Disease
Background/Objectives: Cardiovascular diseases (CVDs), including valvular heart disease (VHD), remain the leading cause of morbidity and mortality in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
Mislav Radić, Hana Đogaš, Tina Bečić, Petra Šimac, Ivana Jukić, Josipa Radić, Damir Fabijanić   +6 more
doaj   +1 more source

A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort [PDF]

, 2010
<p><b>Objectives</b> The aim of this study was to confirm the influence of TNFSF4 polymorphisms on systemic sclerosis (SSc) susceptibility and phenotypic features.</p> <p><b>Methods</b> A total of 8 European ...
A E Voskuyl, A Fernández-Nebro, A Herrick, A J Schuerwegh, A Kreuter, A Nordin, A Pros, B A Lie, B P Koeleman, B Rueda, C Denton, C Fonseca, C P Simeon, C Tolosa, E De Langhe, E Vicente-Rabaneda, F De Keyser, F Houssiau, F J García-Hernández, G Espinosa, G Riemekasten, H Manku, I Castellví, I Gómez-Gracia, J A Román-Ivorra, J M van Laar, J Martín, J Worthington, JCA Broen, K Claes, L Beretta, L Bossini-Castillo, L Padykov, L Rodríguez, M A González-Gay, M C Vonk, M F González-Escribano, M Gallego, M M Chee, M T Camps, M V Egurbide, MJ Gough, MJH Coenen, N Hunzelmann, N Navarrete, N Ortego-Centeno, P Airó, P Carreira, P García de la Peña, P Gourh, P Shiels, R Hesselstrand, R Madhok, R Scorza, R Westhovens, T Witte, TRDJ Radstake, V Follonosa, V Smith, Ø Palm   +59 more
core   +5 more sources

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source