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Frontiers in Plant Science, 2014 Plant roots, which are essential for providing anchorage to the soil, acquiring mineral nutrients and water, and for synthesizing a plethora of metabolites, provide an excellent model for studying physiological, developmental, and metabolic processes at a systems level.
Wolfgang eSchmidt
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Computational Systems Biology [PDF]
The Scientific World Journal, 2013 The complex biological systems consist of distinct molecules that exert their functions by interacting with each other, which makes it a big challenge to understand how the cellular machinery works. Recently, the accumulation of a large amount of multiscale omics data, such as next-generation sequencing data and protein interaction data, provides ...
Xing-Ming Zhao +3 more
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Borges Dilemma, Fundamental Laws, and Systems Biology [PDF]
arXiv, 2007 I reason here that the known folk law in biology that there is no general law in biology because of exceptions is false. The (quantitative) systems biology offers the potential to solve the Borges Dilemma, by transcending it. There have already a plenty of indications on this trend.
Ao, P
arxiv +5 more sources
Resonance, 2018 Systems biology seeks to study biological systems as a whole, contrary to the reductionist approach that has dominated biology. Such a view of biological systems emanating from strong foundations of molecular level understanding of the individual ...
Chandra, Nagasuma, Raman, Karthik
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What is systems biology? [PDF]
Frontiers in Physiology, 2010 Systems biology is increasingly popular, but to many biologists it remains unclear what this new discipline actually encompasses. This brief personal perspective starts by outlining the aesthetic qualities that motivate systems biologists, discusses ...
Rainer Breitling, Rainer Breitling
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Systems engineering to systems biology
Molecular Systems Biology, 2008 Mol Syst Biol. 4: 185 The ‘bottom‐up’ approach to systems biology entails quantitatively studying complex biological processes by analyzing their molecular components. A converse system biology approach is to infer properties of biological systems in a ‘top‐down’ fashion, using a variety of network reverse engineering methods, data‐driven modeling and
Muhammed A Yıldırım, Marc Vidal
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AutoAnalyze in Systems Biology [PDF]
Bioinformatics and Biology Insights, 2019 AutoAnalyze is a highly customizable framework for the visualization and analysis of large-scale model graphs. Originally developed for use in the automotive domain, it also supports efficient computation within molecular networks represented by reaction
Christian Saad +3 more
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Systems biology and cancer, [Editorial] [PDF]
Progress in Biophysics and Molecular Biology, 2011 The systems approach to complex biological problems has rapidly gained ground during the first decade of this century. There are several reasons for this development. An important one is that while the achievement of sequencing the complete human genome,
Ana M. Soto +25 more
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