Results 31 to 40 of about 2,713,734 (236)

Enhanced Operational Semantics in Systems Biology [PDF]

open access: yes, 2003
We are faced with a great challenge: the cross-fertilization between the fields of formal methods for concurrency, in the computer science domain, and systems biology in the biological ...
A. Dovier   +11 more
core   +1 more source

Systems Biology, Integrative Biology, Predictive Biology [PDF]

open access: yesCell, 2005
The pursuit of science is based on empiricism enabled by advancing technologies. Theories then emerge that unify our understanding of natural order. The trinity of experimentation, theory, and technology that underlies the scientific method cannot be placed into a hierarchy of importance.
openaire   +3 more sources

Systems biology of SNPs [PDF]

open access: yesMolecular Systems Biology, 2006
Genome-scale networks can now be reconstructed based on high-throughput data sets. Mathematical analyses of these networks are used to compute their candidate functional or phenotypic states. Analysis of functional states of networks shows that the activity of biochemical reactions can be highly correlated in physiological states, forming so-called co ...
Jamshidi, Neema, Palsson, Bernhard Ø
openaire   +5 more sources

Stochastic Physics, Complex Systems and Biology [PDF]

open access: yes, 2012
In complex systems, the interplay between nonlinear and stochastic dynamics, e.g., J. Monod's necessity and chance, gives rise to an evolutionary process in Darwinian sense, in terms of discrete jumps among attractors, with punctuated equilibrium ...
A Lasota   +45 more
core   +2 more sources

SYSTEMS BIOLOGY. Systems biology (un)certainties.

open access: yesScience (New York, N.Y.), 2015
How can modelers restore confidence in systems and computational biology?
Kirk, PDW, Babtie, AC, Stumpf, MPH
openaire   +2 more sources

Imaging in Systems Biology [PDF]

open access: yesCell, 2007
Most systems biology approaches involve determining the structure of biological circuits using genomewide "-omic" analyses. Yet imaging offers the unique advantage of watching biological circuits function over time at single-cell resolution in the intact animal.
Megason, Sean G., Fraser, Scott E.
openaire   +4 more sources

Borges Dilemma, Fundamental Laws, and Systems Biology [PDF]

open access: yes, 2007
I reason here that the known folk law in biology that there is no general law in biology because of exceptions is false. The (quantitative) systems biology offers the potential to solve the Borges Dilemma, by transcending it.
Ao, P
core   +3 more sources

Systems biology versus molecular biology [PDF]

open access: yesCurrent Biology, 2004
Molecular biology and systems biology provide answers to the same questions, but the answers are quite different for the two approaches and are, on the surface, unrelated. The molecular biological answers are arguably more fundamental and are unique, but alternative systems biology answers are possible – consider the two systems-level answers to the ...
openaire   +3 more sources

Systems engineering to systems biology

open access: yesMolecular Systems Biology, 2008
Mol Syst Biol. 4: 185 The ‘bottom‐up’ approach to systems biology entails quantitatively studying complex biological processes by analyzing their molecular components. A converse system biology approach is to infer properties of biological systems in a ‘top‐down’ fashion, using a variety of network reverse engineering methods, data‐driven modeling and
Yıldırım, Muhammed A, Vidal, Marc
openaire   +5 more sources

Planetary Systems Biology [PDF]

open access: yesMolecular Cell, 2005
Combining paleogenetics, protein engineering, synthetic biology, and metabolic modeling, a planetary biology perspective is brought to bear on adaptive evolutionary events in ancient bacteria.
Department of Chemistry, University of Florida, Gainesville, FL 32611 USA ( host institution )   +2 more
openaire   +4 more sources

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