Results 41 to 50 of about 2,989,026 (346)
Journal of Cell Biology, 2014 Systems cell biology melds high-throughput experimentation with quantitative analysis and modeling to understand many critical processes that contribute to cellular organization and dynamics. Recently, there have been several advances in technology and in the application of modeling approaches that enable the exploration of the dynamic properties of ...
Mast, Fred D. +2 more
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SYSTEMS BIOLOGY. Systems biology (un)certainties.
Science (New York, N.Y.), 2015 How can modelers restore confidence in systems and computational biology? Systems biology, some have claimed ( 1 ), attempts the impossible and is doomed to fail. Possible definitions abound, but systems biology is widely understood to be an approach for studying the behavior of systems of interacting biological components that combines experiments ...
Kirk, PDW, Babtie, AC, Stumpf, MPH
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Simulation-based model selection for dynamical systems in systems and population biology [PDF]
, 2010 Computer simulations have become an important tool across the biomedical sciences and beyond. For many important problems several different models or hypotheses exist and choosing which one best describes reality or observed data is not straightforward ...
Addy +41 more
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IET Systems Biology, 2011 Advances in systems biology are increasingly dependent upon the integration of various types of data and different methodologies to reconstruct how cells work at the systemic level. Thus, teams with a varied array of expertise and people with interdisciplinary training are needed.
R, Alves, E, Vilaprinyo, A, Sorribas
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An oscillating reaction network with an exact closed form solution in the time domain
BMC Bioinformatics, 2023 Background Oscillatory behavior is critical to many life sustaining processes such as cell cycles, circadian rhythms, and notch signaling. Important biological functions depend on the characteristics of these oscillations (hereafter, oscillation ...
Joseph Hellerstein
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, 2013 This is a contribution to the encyclopedia of systems biology on ...
Hüttemann, Andreas, Kaiser, Marie I.
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iScience, 2021 Summary: Recent findings indicate that changes underlying cancer onset and progression are not only attributable to changes in DNA structure and expression of individual genes but to changes in interactions among these genes as well.
Zainab Arshad, John F. McDonald
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Software that goes with the flow in systems biology [PDF]
, 2010 A recent article in BMC Bioinformatics describes new advances in workflow systems for computational modeling in systems biology. Such systems can accelerate, and improve the consistency of, modeling through automation not only at the simulation and ...
A Funahashi +14 more
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Journal of The Royal Society Interface, 2017 Complex systems theory is concerned with identifying and characterizing common design elements that are observed across diverse natural, technological and social complex systems. Systems biology, a more holistic approach to study molecules and cells in biology, has advanced rapidly in the past two decades.
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Systems biology at the Institute for Systems Biology [PDF]
Briefings in Functional Genomics and Proteomics, 2008 Systems biology represents an experimental approach to biology that attempts to study biological systems in a holistic rather than an atomistic manner. Ideally this involves gathering dynamic and global data sets as well as phenotypic data from different levels of the biological information hierarchy, integrating them and modeling them graphically and ...
Leroy, Hood +3 more
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