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Journal of Integrative Bioinformatics, 2022 Visual representations are commonly used to explore, analyse, and communicate information and knowledge in systems biology and beyond. Such visualisations not only need to be accurate but should also be aesthetically pleasing and informative.
Schreiber Falk, Czauderna Tobias
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Current advances in systems and integrative biology [PDF]
, 2014 Systems biology has gained a tremendous amount of interest in the last few years. This is partly due to the realization that traditional approaches focusing only on a few molecules at a time cannot describe the impact of aberrant or modulated molecular ...
Fernandes, Marco +2 more
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Systems biology versus molecular biology [PDF]
Current Biology, 2004 Molecular biology and systems biology provide answers to the same questions, but the answers are quite different for the two approaches and are, on the surface, unrelated. The molecular biological answers are arguably more fundamental and are unique, but alternative systems biology answers are possible – consider the two systems-level answers to the ...
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A metabolic regulatory network for the Caenorhabditis elegans intestine
iScience, 2022 Summary: Metabolic perturbations can affect gene expression, for instance to rewire metabolism. While numerous efforts have measured gene expression in response to individual metabolic perturbations, methods that determine all metabolic perturbations ...
Sushila Bhattacharya +7 more
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Biophysics and systems biology [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2010 Biophysics at the systems level, as distinct from molecular biophysics, acquired its most famous paradigm in the work of Hodgkin and Huxley, who integrated their equations for the nerve impulse in 1952. Their approach has since been extended to other organs of the body, notably including the heart. The modern field of computational biology has expanded
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Foundations of Theoretical Approaches in Systems Biology [PDF]
, 2018 AM-S was funded by the German Ministry of Education and Research (BMBF) projects OpHeLiA (0316197) and HOBBIT (031B0363A). RA funded by Generalitat de Catalunya Consolidated Group SGR133 (2017).
Alves, Rui +2 more
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Population Ecology, EarlyView.In the process of captive breeding and reintroduction of endangered animal species, it is crucial to minimize familial bias in reproductive success during the reintroduction phase to preserve genetic diversity. In this study, we attempted to identify the familial lineage of individuals of the endangered bagrid fish Tachysurus ichikawai born at the ...
Hinano Mizuno +5 more
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iScience, 2021 Summary: Base editing (BE) is a promising genome engineering tool for modifying DNA or RNA and has been widely used in various microorganisms as well as eukaryotic cells.
Tianyuan Su +6 more
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Systems chemical biology [PDF]
Nature Chemical Biology, 2007 The increasing availability of data related to genes, proteins and their modulation by small molecules has provided a vast amount of biological information leading to the emergence of systems biology and the broad use of simulation tools for data analysis.
Oprea, Tudor I +3 more
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Population Ecology, EarlyView.In this article, we tested optimal SNP filtering strategies for accurate parentage assignment and pedigree reconstruction for a wild population of red‐spotted masu salmon, Oncorhynchus masou ishikawae. We found that mid‐point filtering in terms of call rate and minor allele frequency performs well for pedigree reconstruction.
Shohei Noda +6 more
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