Results 51 to 60 of about 25,508,313 (370)

Software that goes with the flow in systems biology [PDF]

open access: yes, 2010
A recent article in BMC Bioinformatics describes new advances in workflow systems for computational modeling in systems biology. Such systems can accelerate, and improve the consistency of, modeling through automation not only at the simulation and ...
A Funahashi   +14 more
core   +3 more sources

The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada

open access: yesPopulation Ecology, EarlyView.
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley   +1 more source

Base editing-coupled survival screening enabled high-sensitive analysis of PAM compatibility and finding of the new possible off-target

open access: yesiScience, 2021
Summary: Base editing (BE) is a promising genome engineering tool for modifying DNA or RNA and has been widely used in various microorganisms as well as eukaryotic cells.
Tianyuan Su   +6 more
doaj  

Controlled vocabularies and semantics in systems biology [PDF]

open access: yes, 2011
The use of computational modeling to describe and analyze biological systems is at the heart of systems biology. Model structures, simulation descriptions and numerical results can be encoded in structured formats, but there is an increasing need to ...
Courtot, Mélanie, Hucka, Michael
core  

Simulation-based model selection for dynamical systems in systems and population biology [PDF]

open access: yes, 2010
Computer simulations have become an important tool across the biomedical sciences and beyond. For many important problems several different models or hypotheses exist and choosing which one best describes reality or observed data is not straightforward ...
Addy   +41 more
core   +3 more sources

Bipartite graphs in systems biology and medicine: a survey of methods and applications

open access: yesGigaScience, 2018
The latest advances in high-throughput techniques during the past decade allowed the systems biology field to expand significantly. Today, the focus of biologists has shifted from the study of individual biological components to the study of complex ...
Georgios A. Pavlopoulos   +5 more
semanticscholar   +1 more source

Network topology drives population temporal variability in experimental habitat networks

open access: yesPopulation Ecology, EarlyView.
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu   +3 more
wiley   +1 more source

Biophysics and systems biology [PDF]

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2010
Biophysics at the systems level, as distinct from molecular biophysics, acquired its most famous paradigm in the work of Hodgkin and Huxley, who integrated their equations for the nerve impulse in 1952. Their approach has since been extended to other organs of the body, notably including the heart. The modern field of computational biology has expanded
openaire   +3 more sources

A yeast chemogenomic screen identifies pathways that modulate adipic acid toxicity

open access: yesiScience, 2021
Summary: Adipic acid production by yeast fermentation is gaining attention as a renewable source of platform chemicals for making nylon products. However, adipic acid toxicity inhibits yeast growth and fermentation.
Eugene Fletcher   +3 more
doaj  

Computational challenges of systems biology [PDF]

open access: yes, 2004
Progress in the study of biological systems such as the heart, brain, and liver will require computer scientists to work closely with life scientists and mathematicians.
Finkelstein, A.   +6 more
core  

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